جستجوی مقالات مرتبط با کلیدواژه « آنتی بادی HBs » در نشریات گروه « پزشکی »

  Hepatitis B is the second leading cause of carcinogenesis after smoking. The purpose of this study was to determine the antibody titer against the hepatitis B virus among employees of a police unit. This cross-sectional study was conducted on 534 employees of a police unit. HBS antibody was measured by ELISA in blood samples. The results of this study showed that 35.5% of the samples did not have the required level of immunity against the hepatitis B virus. Statistically, the level of safety was significant with age, work experience, and type of employment. Considering that more than one thirds of the samples did not have the necessary safety to prevent hepatitis B infection; therefore, staff training about repercussions of such disease and the role of vaccination in preventing disease is necessary.

Hepatitis B is a bloodborne infections and it is predicted that about two billion people in the world have been exposed to the hepatitis B virus. Because of occupational reasons, medical students and staffs are more susceptible to expose to this disease than other members of society.
This study is a descriptive-analytic study and 238 staffs and students of Sabzevar University of Medical Sciences were randomly selected and sampled. Then, the antibody titer of surface anti-protein of hepatitis B virus (HBs- Ab) was measured using ELISA method and the results were analyzed using the software Stata 12 after recording the demographic results and information.
Out of 238, 156 persons were female ( 65.5%) and 82 persons ( 34.5%) were male. 66% of individuals had antibody higher than 10 mu/ml and 37.4 % of individuals showed the appropriate answers higher than 100 u/ml. The relationship between job, sex and marital status with the immune response was significant. 100% of people who received full dose along with the booster vaccine were immune. Over time, the percentage of immune people has been decreased.
Considering the reduction of response to vaccines over time and healthcare personnel being at risk, it is recommended that antibody titer was periodically examined in these individuals in 5 to 10 years to administer a booster dose in the case of a decrease in antibody titers.

Hepatitis B (HB) is one of the main health problems. Over 400 million people worldwide have been evaluated as infected patients or chronic carriers. Health care workers (HCWs) are of higher risk for infectious diseases including HBV infected patients. This study aims to evaluate the rate of HBS antibody among the HCWs of Shahid Sadoughi Burn hospital in Yazd. This cross sectional descriptive study was conducted on 52 staff of the hospital approved vaccinated against HBV. HBS antibody was measured by ELISA in blood samples. Anti HBS titer of more than 10 lu/ml was considered positive. Collected data were analyzed by SPSS (16) software using descriptive data analysis and Fisher exact test. Among the 52 vaccinated staff of the hospital، 90. 4% subjects had positive titers but 9. 6% were negative. Females had higher titers (96%) than the males (85. 2%). There was not a statically significant correlation between age، sex، accurate vaccination intervals and titer of HBS antibody، (P >0. 05)، but a positive correlation was found between duration after the last dose of vaccine and titer of HBS antibody (P= 0. 046) More than 90% of the HCWS had immunity against HBV. Considering the importance of health care workers in transmission of blood born infections، a booster dose of hepatitis B vaccine should be delivered to those not having acceptable HBS antibody titer against HBV.

Hepatitis B virus is the cause of acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Its prevalence has been reported to be 0.1%-0.5% and 1.6%-6.5% in the United States and Iran respectively. At present, the only sure preventive measure is vaccination but it does not create absolute (100%) immunity. Antibody production is between 79% to 90%, which occurs three days after vaccination. Antibody level decreases as time goes by. The present study was done aiming at determining immunogenicity due to complete hepatitis B vaccination in the nursing staff and its relationship with variables such as age, sex, body mass index, working place, and period of time elapsed after the last dose of vaccine. This descriptive cross sectional study was done in 2004 on 112 nursing staff of Birjand Medical Sciences University hospitals "Vally-e-asr" and "Imam Reza", who had been vaccinated three times and two months to five years elapsed after their last vaccination. First, 4 ml of blood was taken from each subject as their personal information was recorded in a questionnaire. Then, the samples were quantitatively measured by means of Italian Radium Kits using Anti-HBs ELISA. The Study revealed that antibody titer was over 10 mIU/ml in 88.4% of the subjects.11.6% did not have protective antibody but its level was relative and appropriate in 12.5% and 75.9% respectively. There was no significant correlation between HBs-Antibody level and variables such as sex, age, ward, and body mass index in the subjects (P>0.05). Regarding that 11.6% of the subjects did not have protective antibody at all it is suggested that anti-HBs level should be measured in the nursing staff and non-immune- ones must be revaccinated.

Vaccination is one of the most effective ways in preventing the hepatitis B viruse. This study was done to evaluate the response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran. This cross-sectional descriptive study was carried out on 215, children of 7-12 month of age (55.3% male, 44.7% female), in Gorgan, northern Iran during 2006. These subjects already had received the three-time vaccination against hepatitis B. Anti-HBs, Anti-HBc and HBsAg level of these children serum were determined, using ELISA technique. In 30 (14%) subject's serum, there was not detected any antibodies against the viruses. Out of 185 children positive for HBS, 4 cases belong to HBC viruses. As a whole, 86% of the samples, had more than ten international unit of HBS. The meanSD of the titred antibodies in male and female were 158.84 12 and 187.55 b13.83 respectively. The response not to three-times vaccination in male and female were 84% and 89.9% respectively. This study showed that in spit of vaccination, there are cases with virus-contamination. The reasons for absence of any response to the vaccination in some of this children can be due to deficiency in the immune system, improper genetic background which can not be stimulated by that vaccination, inadequate proper conditions for the preservation of vaccine, and the type vaccine used. Also the procedure of vaccine inoculation, the vaccine preservation condition and transportation should be taken into considertion.