جستجوی مقالات مرتبط با کلیدواژه « Golestan Province » در نشریات گروه « پزشکی »

Colorectal cancer is the third most common type of cancer in terms of incidence and the second most common cause of cancer-related death worldwide. The aim of this study was to investigate the expression of CTGF and MLH1 gene in colorectal cancer tumor tissues and adjacent normal tissues in patients in Golestan province.

In this experimental study, 20 colorectal cancer tissue samples and 20 adjacent healthy tissue samples were collected from Sayad Shirazi Hospital Research Center, Gorgan. After RNA extraction, cDNA synthesis and primer design, the expresion of CTGF and MLH1 genes were measured by Real Time PCR. Statistical analysis of data was done in Graphpad Prism software.

According to findings, increase was seen in the CTGF gene expression level in tumor tissue to the adjacent healthy tissue (P<0.05), while the ratio of the MLH1 gene expression in the tumor tissue to the adjacent healthy tissue decreased (P<0.05).

This study showed that increased expression levels of CTGF gene and decreased expression levels of MLH1 gene play roles in colorectal cancer.

 In order to maintain and improve older adults’ health, the integrated and comprehensive geriatric care program has been developed and run by ministry of health. The present study was conducted to evaluate the effectiveness of this program on physical and mental health of older adults in Golestan province in 2019.

Methods & Materials: 

The present retrospective cohort study employed a multistage clustered random sampling technique to obtain 500 e-health records of older adults during 2017-2019. The data on blood pressure, depression, and BMI were extracted from e-health records. Data analysis was conducted using repeated measure anova, paired t-test and Wilcoxon tests. The SPSS statistics software v. 20 was used to perform data analysis

 Of the 500 cases studied, were male and female, respectively. The Mean±SD age of the participants was 69.97±7.45 years. The results of inferential statistics showed that the mean score of systolic blood pressure was significantly decreased through study period (P<0.001). However, through study period depression score was significantly increased (P≤0.05). There was no significant difference in BMI index.

 The results of this study showed that the integrated and comprehensive geriatric program was effective for controlling blood pressure, however was not effective for preventing depression. Therefore, stakeholders should pay more attention towards establishing appropriate program to improve older adults' mental health.

The World Health Organization considers the implementation of the referral system to be a key step in improving the quality of services in health care systems. The purpose of this study was to explain the executive challenges of the electronic referral system in Golestan Province, Iran.

A qualitative study was conducted in Golestan Province, Iran in 2019 with a content analysis approach. The participants were family physicians, specialists, university staff managers, responsible health officers in the Offices of Deputy Ministers of Health, the General Directorate of Health Insurance, Department of Information Technology, Rural Health Network managers, health network managers and patients selected purposefully. Data were collected through semi-structured interviews and analyzed using the content analysis method.

The main challenges of giving appointments to patients included the lack of time of family physicians, the irregular presence of specialists, difficulty in getting an appointment, and reverse referrals. As regards referrals and waiting times, the main challenges were found to be the lack of sufficient admissions following cancellation of the health insurance contract with the private sector, the delay of physicians in attending the health centers, long waiting times to be visited, and writing the feedback by the physicians. In addition, the main challenges of the visits and diagnosis included the short visiting times, the higher quality of the specialistschr('39') visits in the private sector, and the lack of clear guidelines. Finally, the main challenges as regards giving feedback were the reluctance and noncommitment of some specialists to provide feedback, as well as the low quality and lack of usability of the feedbacks given.

Based on the findings of this study, the following actions and measures may help improve the current situation as regards the current referral systems: allocating sustainable resources; allocating financial credits; designing and implementing a reward and punishment system; reforming the queuing system; empowering medical students; and equipping specialists with electronic pens for giving written feedback.

Identification of the pattern and causes of death and dealing with its etiological factors is one of the most fundamental principles of planning, management and evaluation, and accountability in the health sector. This study aimed to study and analyze one of the critical phenomena (i.e., death) in Golestan Province.

In this study, we used the secondary analysis method and collected data by the census. The statistical population included all cases of death registered at GDR of the deputy of the health of Golestan University of Medical Sciences in 2018. Death indicators were calculated using WinPepi version 11.65, and linear diagrams were drawn in Excel 2016. In addition, the relationship between various causes of death was assessed in SPSS version 23 using Chi-square.

In this study, the three leading causes of death were reported to be cardiovascular diseases, cancers, and external factors, respectively. In terms of gender, the death rate was 1.3 higher in men, compared to women. In addition, the highest percentage of death was related to the age range of more than 80 years. Moreover, the highest rate of specific causal damping and proportional damping was for diseases of the cardiovascular system and the lowest was related to mental and behavioral disorders. Furthermore, the highest specific causal and proportional damping rate were related to cardiovascular diseases, whereas the lowest rate was observed in cases with psychological and behavioral disorders.

In 2018, less than a quarter of the deceased was aged≤52 years, which may explain the high average age of the dead in the province. Continuous studies in determining the level of mortality, its effective causes, and awareness of epidemiological changes are necessary for more accurate planning, maintenance, and promotion of health in any society.

Background and

Despite appropriate prevention and therapeutic activities in recent years, Pulmonary Tuberculosis (TB) is still one of the top ten causes of mortality in the world. The purpose of this study was to analyze the distribution of pulmonary tuberculosis in cities of Golestan province, Iran and identifying the major determinants of this disease.

from 8374 TB cases was recorded in TB Registry Program in Golestan province between 2007 and 2016 we analyzed the information of 5648 new cases. Data was analyzed in SPSS 24 and Stata 13. Mean ± SD and frequency table were applied for quantitative and qualitative variables, respectively.

The standardized incidence rate of TB in 100,000 population in Golestan province was 41.29 and in males and females it was 41.40 and 41.22, respectively, indicating no significant differences between them (p< 0.34). TB hazard ratio was found to be 62% higher in rural areas (p< 0.001). The standardized incidence rates in urban and rural areas were 31.63 and 51.36 in 100,000 population, respectively. Ramyan and Gomishan had the highest and lowest incidence rats of TB, respectively (77.68 and 14.88 in 100,000 population, respectively).

According to current findings, screening for TB in rural areas in Golestan province is highly recommended. Eastern regions of the province are at greater risk for TB infection due to their ethnic composition (Sistan and Baluchestan immigrants)