جستجوی مقالات مرتبط با کلیدواژه « Prevalence of Resistance » در نشریات گروه « پزشکی »

The prevalence of self‑medication is high in Bangladesh due to easy access and poor regulatory controls over these drugs. Our study aimed to assess the attitude of university students in Bangladesh toward antibiotic usage, especially their knowledge and awareness about antibiotics and their resistance. We also evaluated the determinants behind their attempts at drug intake without prescription.

A cross‑sectional study was conducted in Mawlana Bhashani Science and Technology University that included information from randomly selected 200 students from 15 departments using a structured questionnaire. The statistical analyses were performed by using SPSS software (version 21) and R programming.

The study revealed that 61.0% of the students use self‑medication at different times or always; 32.5% of the respondents keep antibiotics for future use, and 38% of the students think it is right to stop antibiotics when symptoms are improving. Half of the participants (47.5%) use antibiotics based on their previous experience. The criteria of antibiotic selection have a significant relationship with knowledge about antibiotic resistance (P = 0.017) and altered prescribed medicine without doctor’s advice (P < 0.001). The multivariate analysis indicates that respondents who know about antibiotic resistance select antibiotics from the community pharmacists with respect to their own experience 5.102 times higher than those who do not know about antibiotic resistance.

The study mainly explored the knowledge gaps of the students on the options that are responsible for antibiotic resistance in the community and found that students have mid‑level knowledge (66%) about antibiotic resistance.

Acinetobacter baumannii is one of the most important opportunistic pathogens responsible for several nosocomial infections. A major problem in treatment is antibiotic resistance.
By searching international and national databases, including PubMed, Google Scholar, Web of Science, SID, Magiran, IranDoc and IranMedex, 38 articles between years 2002 to 2016 published world-wide were extracted and analyzed using the meta-analysis method and random effects model. The heterogeneity of studies was assessed using the I2 index. Data were analyzed with the R and STATA (Ver 11/2) software.
Forty-three articles were selected for this study. Drug-resistance of Acinetobacter baumannii towards Polymyxin was reported as 5%, yet for Colistin 4% was estimated. Resistance rates to Polymyxin and Colistin in the continent of America and Asia was 6% and Sensitivity rate to Polymyxin and Colistin was 96% and 80%, respectively.
Given that drug resistance rate of Acinetobacter baumannii to Polymyxin and Colistin in this study was 5% and 4%, respectively, thus indicating high sensitivity of Acinetobacter baumannii to these antibiotics, this group can be administered as appropriate therapeutic agents against these bacteria.