مجله دانشکده پزشکی اصفهان
پیاپی 321 (هفته اول فروردین 1394)

Birth weight is probably the most important factor affecting neonatal mortality and morbidity. Compared with normal weight infants, low-birth-weight (LBW) infants may be more at risk for many health problems. The prediction of low birth weight is important as it may cause mental and physical health problems in childhood and adulthood. We assessed a computer-aided diagnosis system to classify infants to low or normal birth weight categories. In the present study, the association between the low birth weight and the intake of about 40 types of macro- and micronutrients during the first (1st Tr), second (2nd Tr.) and third (3rd Tr.) trimesters was assessed based on demographic and reproductive characteristics, physical activity and nutrients intake in pregnant women. The dataset used in this study contained 526 pregnant women with 95 input features. The used classifiers were k-Nearest Neighbors (kNN), Probabilistic Neural Network (PNN), and two Adaptive Neuro-Fuzzy Classifiers (ANFC-SCG: Scaled Conjugate Gradient, ANFC-LHs: Linguistic Hedges). Also, sequential feature selection (FS) was applied on the low birth weight risk factors to reduce the feature space. The accuracy of the classifiers kNN, PNN, ANFC-SCG and ANFC-LHs were 48%, 50%, 50% and 50% without feature selection and 93%, 83%, 80% and 83% with feature selection, respectively. Among the tested classifiers, the statistical power and type I error (α) of the best configuration (FS-kNN; k = 3) were 96% and 0.10 in the Leave-One-Out validation framework, showing that the proposed diagnosis system is clinically reliable. Also, using Leave-One-Out cross-validation, the guarding against Type III error was granted.

Nowadays, bio-psycho-social model is the best model for the assessment and treatment of functional gastrointestinal disorders. This study aimed to evaluate the structural pattern of the relationships between the difficulties in emotion regulation, psychological problems (anxiety and depression), somatization and gastrointestinal symptoms intensity in patients with functional gastrointestinal disorders.

240 patients with functional gastrointestinal disorders were selected using convenience sampling method. They participated in the research by filling four questionnaires: Difficulties in Emotion Regulation Scale (DERS), Hospital Anxiety and Depression Scale (HADS), Modified Somatic Perception Questionnaire (MSPQ) and Gastrointestinal Symptom Rating Scale (GSRS). Data were analyzed using structural equation modeling method.

The difficulties in emotion regulation had significantly direct effects on anxiety, depression and somatization, and indirect effect on gastrointestinal symptoms intensity (P < 0.001). Besides, the mediatory roles of anxiety and somatization in the relationship between the difficulties in emotion regulation and gastrointestinal symptoms intensity were supported.

In sum, the results of the study emphasize the role of difficulties in emotion regulation in development of gastrointestinal symptoms intensity in these patients by increasing anxiety and somatization.

Lateral epicondylitis is a common disease that in some instances does not respond to the usual treatment, even after different treatment efforts. Management of lateral epicondylitis is firstly based upon the conservative treatments and local injection of steroids; but if radial tunnel syndrome presented coincidently, alternative management must be planned on surgical decompression of radial nerve. As a result, diagnosis of cases with radial tunnel syndrome and tennis elbow simultaneously is significantly important for the planning of the management. The aim of this study was to determine the coincidence of radial tunnel syndrome with tennis elbow. In a cross-sectional study, 52 patients with confirmed lateral epicondylitis who referred to orthopedic clinic of Kashani hospital (Isfahan, Iran) during 2013-2014 were studied. The coincidence of lateral epicondylitis and radial tunnel syndrome was investigated among them via clinical examination and electromyogram (EMG) and nerve conduction velocity (NCV). In physical examination, coincidence of lateral epicondylitis with radial tunnel syndrome was seen in 24 patients (46.2%); according to EMG and NCV tests, this coincidence was seen in 19 patients (36.5%). Coincidence of lateral epicondylitis with carpal tunnel syndrome and lateral epicondyle of elbow sclerosis was seen in 4 (7.7%) and 7 patients (13.5%), respectively. Coincidence of radial tunnel syndrome with lateral epicondylitis is of high prevalence. So, it is necessary to conclude radial tunnel syndrome as the first diagnosis when faced to a patients suffering from tennis elbow who does not respond to usual conservative treatments; for these patients, supplementary paraclinical tests may be needed.

A number of different cellular sources of neural stem cells have been identified. These sources include stem cells at the retinal margin, pigmented cells in the ciliary body and iris, non-pigmented cells in the ciliary body and Müller glia within the retina and also embryo and adult neural stem cells (NSCs). In the present review, we discuss the combinations of growth factors that are capable of stimulating the proliferation and making of neurons from stem cells, neural progenitors, non-neural epithelial cells, and postmitotic support cells.