مجله دانشگاه علوم پزشکی بابل
سال هجدهم شماره 10 (پیاپی 109، مهر 1395)

Stress urinary incontinence (SUI) occurs in 35% of women and about 30% of them will require a second surgery. This illness has negative effects on patients’ quality of life. Since TVT(Tension-free vaginal tape) bladder neck suspension is a minimally invasive procedure for curing patients with stress urinary incontinence, the present study was conducted to investigate the effect of TVT bladder neck suspension on quality of life in these patients.
This analytical study was conducted to assess the quality of life in 50 patients with stress urinary incontinence, using Kings Health Questionnaire in various fields, before TVT surgery, one month after surgery, and six month after that. This questionnaire has a 4-point grading system. Each field is graded from 0 (best) to 100 (worst). Decline in scores indicates increase in quality of life.
FINDINGS: Every field that influenced the quality of life in women with stress urinary incontinence was improved significantly, one and six month after TVT surgery compared with the situation before the surgery (p Results of the study demonstrated that TVT bladder neck suspension improves the quality of life in patients with stress urinary incontinence.

Copper is a metal element which plays a pivotal role in the pathology of various neurological disorders including cognitive disorders. Previous studies have shown different relationships between serum levels of copper and cognitive impairment. This study aimed to investigate the relationship between serum levels of copper and cognitive disorders in the elderly in Amirkola.
This cross-sectional study is a part of Amirkola Health and Ageing Project performed on all the population is 60 years and older. According to the Mini-Mental State Examination (MMSE), people were divided into two groups with impaired cognitive status (N=347) and normal (N=657). People with cognitive impairment were classified in mild, moderate, severe subgroups. In this test, point more than or equal to 25 (30-25) was considered as natural and score less than 25 as a person with cognitive impairment. Serum copper level was measured in venous blood samples and was compared between two groups.
FINDINGS: In this study, of 1616 elderly people, 1004 people in the age group 60-90 years were examined. 518 men and 486 women were existed with a significant difference in serum level of copper between the sexes (p The results showed that cognitive impairment is associated with serum levels of copper

Premature rupture of membranes (PROM) is a serious complication during pregnancy, which is accompanied by prenatal, neonatal and maternal complications including premature delivery, infection and fetal death. The Purpose of this research is to study the frequency of maternal risk factors and neonatal complications of premature rupture of membranes.
This cross-sectional study was conducted on 309 infants with premature rupture of membranes (more than 18 hours before delivery) from 2009 to 2015. After confirming premature rupture of membranes based on history and speculum examination, a questionnaire containing pregnancy information, delivery information and infant profile was completed and assessed.
FINDINGS: Maternal risk factors included diabetes (23 cases, 12.7%), hypertension (17 cases, 9.5%), smoking (16 cases, 8.9%), history of premature rupture of membrane (16 cases, 8.9%), urinary tract infection (13 cases, 7.2%), thyroid disorders (9 cases, 5%), previous premature birth (8 cases, 4.4%) and cerclage (7 cases, 3.8%). Delivery complications included cesarean (117 cases, 38.1%), oligohydramnios (61 cases, 33.9%), chorioamnionitis (14 cases, 11.6%), placental abruption (17 cases, 9.5%), fetal distress (6 cases, 3.3%), intrapartum fever (6 cases, 3.3%) and placenta praevia (5 cases, 2.8%). Neonatal complications included immaturity (165 cases, 73%), jaundice (108 cases, 59%), neonatal infection (94 cases, 52%), respiratory distress syndrome (65 case, 30.4%) and asphyxia (52 cases, 17%). There was a significant difference between infants with infection and without infection in terms of first and fifth minute Apgar scores, erythrocyte sedimentation, platelet and gestational age (p=0.000).
Results of the study demonstrated that diabetes and hypertension are the most frequent maternal risk factors of premature rupture of membranes. Immaturity, respiratory disorders, asphyxia and infection are the most serious associated problems. It may be possible to reduce neonatal problems with proper measures and management

BACKGRAUND AND : Gastroenteritis caused by salmonella is common in humans as a public health problem in the world. The aim of the current study was, detection of agfA and mgtC genes in the Salmonella Typhimurium strains isolated from stool samples using multiplex- PCR method and determination of their antibiotic resistance patterns.
This cross-sectional study on Salmonella typhimurium isolated from children with gastroenteritis admitted to Children's Medical Center of Tehran. Multiplex-PCR using the gene frequency was evaluated by agfA and mgtC . As well as using the gel diffusion method according to CLSI guidelines antibiotic susceptibility of these isolates were studied.
FINDINGS: Of 200 stool collected samples, 60 (30%) Salmonella Typhimurium isolates were obtained. Molecular analysis showed that 24 isolates simultaneously possess both genes were agfA and mgtC. the 52 isolates carries mgtC gene and 40 were have agfA gene. Determination of antibiotic susceptibility pattern in this case is that all isolates (100%) were sensitive to the Ciprofloxacin. So, 85% strains were resistance to nitrofurantoin..
CONCLUSTON: The study concludes that the most frequent virulence genes in these strains, mgtC with the (86/6%) and the lowest prevalence of virulence genes, agfA to the (66/6%) . Result that was above isolates were susceptible to ciprofloxacin 100% and the most resistant to nitrofurantoin was 85%.

Hereditary metabolic diseases are individually rare disorders, early diagnosis and treatment are very important which can prevent from permanent damage to the nervous system and mental retardation and other irreparable injury and even death in these patients. This study was done to evaluate the prevalence of hereditary metabolic diseases in children admitted to Amirkola children hospital 1384-94.
In this cross-sectional study, medical records of patients with hereditary metabolism disorders from 1384 to 1394 were studied. Related information to age, gender, family relationship, family history, disorder type, diagnostic criteria and disease outcome were extracted and analyzed.
FINDINGS: In this study, 65 children were diagnosed with different types of metabolic disease research. The common disorders were maple syrup urine disease 14 patients (21.5%), methylmalonic acidemia 10 (15.3%), mitochondrial 8(12.3%) galactosemia 6(2.9%), respectively. Among children, 36 cases (55.4%) were male and positive family history of metabolic disorders was observed in 15 children (23.1%). Mortality of metabolic disorders was in 26 children (40%) and the rest of the 19 children (54.2%) had developmental delay.
In this study 19 different types of hereditary metabolic diseases were detected that more than 25% of patients had a positive family history of this disorder.