Journal of Inflammatory Diseases
Volume:19 Issue: 3, 2015

Human cytomegalovirus (HCMV) may play a role in the development of glioma disease that is one of the most common brain tumors. The aim of this study was to detect human CMV in patients with glioma in Imam Khomeini hospital، Tehran. This experimental study was conducted on paraffin-embedded tumor samples of 18 patients referred to Imam Khomeini hospital in 2012. Immunohistochemistry (IHC) was performed with monoclonal antibody specific for HCMV PP65 protein and the samples were assessed using a light microscope. Of 18 patients، 13 (72. 2%) were positive for HCMV PP65 protein and four of them expired. With regards to the results، more comprehensive studies are recommended for detection of HCMV in patients with glioma using different diagnostic methods.

The effects of non-invasive physical agents on wound and bone fracture healing have been considered by investigators of different medical fields. Several studies have been conducted about the effects of magnetic field on bone fracture healing. The purpose of this study was to investigate the effects of pulsed magnetic fields on healing of tibial bone lesion in rabbits. This experimental study was performed in Shahid Beheshti University of medical sciences in 2014. Eight New Zealand male rabbits were divided into control (with bone lesion) and experimental (with bone lesion and under pulsed magnetic field therapy) groups. A 4×10 cm bone lesion with 2 mm depth was made by surgery on both tibias of each rabbit. One month after surgery, the rabbits in the experimental group underwent 75 Hz pulsed magnetic field therapy with 4 mT intensity in lesion site for 30 days and 4 hours a day. Forty, 50 and 60 days after surgery, bone healing was evaluated with digital radiographs and bone density was measured in lesion sites. Data were analyzed using T- test. Mean relative bone density in lesion sites was 138.50, 150.73 and 168.30 for 8 bit grey scale in the experimental group during three consecutive imaging and showed %17.89, %15.46 and %16.59 increase in comparison with the control group. With regards to the results, it seems that pulsed magnetic field therapy improves healing of bone fracture through increasing bone density in fracture site and can be used after orthopedic surgeries.

Knee osteoarthritis is one of the most prevalent chronic disorders. Several pharmacological and non-pharmacological approaches have been used to treat knee osteoarthritis. The aim of this study was to determine the effects of adding vitamin B to Diclofenac on pain due to knee osteoarthritis. This double-blind clinical trial was carried out on 73 patients with knee osteoarthritis referred to the Rheumatology and Orthopedics clinics of Shahrekord University of Medical sciences in 2013. The patients underwent treatment with oral Diclofenac plus oral vitamin B (38 patients), or oral Diclofenac plus placebo (35 patients). Pain was measured by the visual analogue scale (VAS) and morning stiffness and physical functioning were measured by the Western Ontario and McMaster Universities Arthritis Index (WOMAC) before treatment, and 14 and 21 days after treatment. Data were analyzed using Chi-square test, T-test, and repeated measures ANOVA. The visual analogue WOMAC mean score for knee pain, overall pain severity, stiffness of knee joint, and function in the last 48 hours significantly decreased in both groups from the first to third measurement. Decrease in overall pain severity, function in the last 48 hours and stiffness of knee joint scores in vitamin B group was more than Diclofenac group. Decrease in knee pain VAS was similar in both groups. Patient satisfaction was not significantly different between the two groups. With regards to the results, it seems that vitamin B supplement is useful for the treatment of osteoarthritis symptoms.

Nutrition and access to it are important aspects of poverty analysis in multidimensional perspective. Measurement of nutritional poverty indices is important to inform policy makers about distributive effects of policy strategies on household and child welfare. The aim of this study was to determine nutritional poverty trend in children of urban and rural areas in Kerman province from 1984 to 2012. This trend analysis was conducted in Kerman Province during 2013. The nutritional poverty trend was measured in children of urban and rural areas using the data from the income-expenditure survey. Food calorie and the Foster, Greer and Thorbecke index were measured in the households. Childhood was divided into four age groups. Data were analyzed based on the ratio, gap and severity of poverty. The nutritional poverty rate was different across the age groups in urban and rural households with child. The highest nutritional poverty was found in 2009 in both urban and rural households. The nutritional poverty rate in 0-5 year’s old age group was lower than the other age groups in both urban and rural areas and in most years. Nutritional poverty was higher and more severe in rural areas compared to urban areas. With regards to the results, provincial and regional policy makers should more emphasize on nutritional poverty reduction in rural areas.

Escherichia coli (E. coli) is the most important cause of urinary tract infections in hospitalized patients especially in intensive care unit (ICU). Colonization of E. coli and its attachment to uroepithelium are mediated by adhesins such as type 1 (fimH) and P (papC) fimbriae. The aim of this study was to determine the frequency of type 1 and P fimbriae-encoding genes among uropathogenic E.coli in ICUs. In this descriptive study, 120 clinical isolates of uropathogenic E.coli were collected from patients with urinary tract infection in ICUs of Qazvin and Karaj hospitals during 2013 and 2014. All bacterial isolates were identified by standard laboratory methods and the fimH and papC genes were detected using the PCR method. Forty (33.3%) isolates were positive for fimH gene and 5 (4.2%) isolates were positive for papC gene. Sixty six (55%) isolates were positive for both genes, and 9 (7.5%) isolates were negative for them. The findings of this study showed the high frequency of type 1 and P fimbriae among uropathogenic E.coli isolates from ICU patients in the studied hospitals.

Treatment of waste air containing volatile organic compounds (VOCs) using cheap and environmentally friendly methods is one of active fields in air pollution control. The aim of this study was to treat air containing triethylamine (TEA) vapor using biotrickling filter inoculated with microbial species decomposing TEA. This experimental study was conducted in the School of Health affiliated to Qazvin University of Medical Sciences in 2014. Biotreatment was performed with biotrickling filter inoculated with microbial species decomposing TEA for two months. The biotrickling filter was set up with air containing TEA as the sole source of carbon, at Empty Bed Residence Times (EBRT) of 36 sec, and inlet concentration of 84 ppm. Data were analyzed using descriptive statistics. Treatment of TEA contaminated air was made after an adaptation period of 11 days. Despite an increase in mass loading to 111 g/m3/h, TEA was eliminated with 109 g/m3/h capacity and 94-100% removal efficiency by zero order kinetics. Elimination capacity and removal efficiency were close to each other and confirmed109 g/m3/h as loading region with critical elimination capacity. With regards to the results, it is possible to treat air containing TEA vapor in biotrickling filter.

The tuberculin test is one of the available tests to detect latent tuberculosis. The aim of this study was to determine the prevalence of latent tuberculosis in students of Qazvin University of Medical Sciences. This cross-sectional study was conducted in a total of 213 medical sciences students by census method in 2014. The tuberculin test was performed for all students. Induration of 10 mm or greater was considered as positive. Data were analyzed using Chi-square test, T-test, Pearson’s correlation coefficient and regression analysis. The prevalence of latent tuberculosis was 14.6%. The mean induration in students with history of exposure to tuberculosis was significantly different from students without history of exposure. The association of exposure to tuberculosis and positive tuberculin test was statistically significant. Age and body mass index were poorly correlated with the size of induration (r= 0.166 and 0.146, respectively). In the regression analysis, only contact with tuberculosis patients was independent predictor of positive tuberculin test. With regards to the results, it seems that the most important factor for positive tuberculin test is a history of contact with tuberculosis patients in medical sciences student. Increasing mean induration size with age may be due to increased contact with subjects infected with tuberculosis.

In the past decade, pulmonary dysfunction has been reported due to treatment with anti-thymocyte globulin (ATG) in patients suffering from rejection of organ transplantation or aplastic anemia. Cytomegalovirus (CMV) infection is one of the common infections in recipients of organ transplantation. In this report, a 46 years old man underwent treatment with ATG due to rejection of kidney transplantation and developed pulmonary infiltration. Cytomegalovirus antigen load was raised in the serum. After discontinuation of ATG and treatment with ganciclovir, fibrosis and reduction of lung volume was developed. The resultant fibrosis was completely resolved after one month and the general condition of the patient was improved. In conclusion, fibrotic pattern in pulmonary HRCT cannot prove the irreversibility of the lesion.

The aim of this study was to compare the effects of lecture and team based learning (TBL) on oral and maxillofacial pathology learning in dental students. This quasi-experimental study was conducted in 30 dental students who applied for oral and maxillofacial pathology course in the School of Dentistry affiliated to Qazvin University of Medical Sciences during the first semester in 2013. The course was consisted of 10 one-hour sessions. Firstly, TBL was used in 5 continuous sessions. Then lecture was used in the remained sessions. In two sessions, multiple choices test was taken for both methods before and after the teaching and without prior notice. The mean difference of pre-test and post-test was 10.28 and 8 in the TBL and lecture, respectively and the difference was not statistically significant. With regards to the results, the effects of lecture and TBL on students’ learning are not significantly different.

The aim of this study was to determine the effects of training on anxiety in mothers of hospitalized children with urinary tract infection. The study was conducted in 40 mothers of hospitalized children in the Qazvin children hospital, during 2012-13. The subjects were selected by random sampling method and were divided into intervention and control groups. Data were collected through the Spielberger Anxiety Inventory on admission and two days before discharge. This questionnaire measures State anxiety and Trait anxiety subscales. Data were analyzed using paired T-test and independent sample T-test. Training had a significant effect on State anxiety in mothers of hospitalized children with urinary tract infection but did not affect Trait anxiety.