فصلنامه یافته
سال هجدهم شماره 2 (پیاپی 66، تابستان 1395)

The most important factors affecting nutritional status of infants and its improvement is mothers’ knowledge, attitude and practice regarding proper nutrition of their children. This study aimed to assess knowledge, attitude and behavior practice of mothers having children of 6-36 months in health centers of Khorramabad on proper feeding of their children.
In this cross- sectional descriptive-analytic study , information of 302 mothers of 6-36 months children referred to health centers in Khorramabad were collected thorough maternal health records and interview records , and data were analyzed using SPSS 21 software, chi-square test, Spearman and Pearson correlation coefficient.
Based on the findings and obtained scores by mothers, 69.9% of the women had good knowledge,69.9% had good attitude and 64.6% had good practice on proper nutrition for their children. There was a significant relationship between mothers’ attitude and education, fathers’ education and mothers’ occupation. There was a significant relationship between fathers’ level of practice, job, number of children, and birth order. There was no significant relationship between the attention level to mass media and attitude and knowledge score, but there was a significant correlation with practice. There was no significant relationship between mothers’ knowledge and education, fathers’ education, mothers’ job, fathers’ job, income, number of children and birth order.
According to the results, the level of knowledge, attitude and practice in mothers is in a good level, but due to the potentional role of father in mother,s practice, it seems that a family based educational programs in health centers, hospitals and mass media is necessary.

Healthy water passes through the pipelines from supply resources to consuming places in which passing from these stages may cause some cases of contamination like heavy metal contamination. Therefore, the aim of this study was to evaluate the contamination of heavy metals (copper, lead, zinc, cadmium, iron, and manganese) in water resources of Nurabad city of Lorestan in 2013.
In this cross-sectional study, samples were collected from 7 wells of drinking water and 2 water storage tanks during 6 months in Nurabad. So that, heavy metal parameters such as copper, lead, zinc, cadmium, iron, and manganese were measured using an atomic absorption device and also electrical conductivity, sulfate, chloride and total dissolved solids were also measured in accordance with standard methods.
Results indicated that the concentration of studied metals in water sources was lower than the national standards and World Health Organization standard, and in the water supply system the concentration of some metals was more than standard level. Moreover, the results showed that the concentration of studied heavy metals were more in winter than in autumn.
Generally, in the water resources of Nurabad city the concentration of studied heavy metals was lower than the national standards and World Health Organization standard and there are not problems for water consumers. However, due to public health and the presence of a high concentration of these metals in the distribution supply, the heavy metal concentration in drinking water of this region should be monitored regularly by responsible organizations.

Preterm delivery is one of the most common causes of perinatal mortality around the world. The purpose of this study was to determine the effect of clindamycin vaginal cream in the prevention of preterm labor.
This study was a control trial carried out on 236 pregnant women, referred to private practice office of a physician,with 13-20 weeks of gestational age. Samples of vaginal smear were gathered, and in the case of abnormal results, subjects were randomly assigned to either a control or case group. Clindamycin group treated with vaginal cream for three nights in the first turn and seven night at the second turn. But the control group received no treatment. Then, all subjects were followed up. Data wero collected using a questionnair and analyzed.
The incidence of premature birth in the control group was higher than the group under treatment with clindamycin (12% vs 7%), but this difference was not enough to be statistically significant. It was also shown that the higher incidence of preterm delivery in the control group was lower than the age of pregnancy termination. Mortality in the control group was significantly higher than the control group.
Although no significant difference was observed in the rate of preterm labor between the two groups, but in control group gestational age was less and mortality rate was high. It seems that clindamycin in decreasing prenatal mortality is associated with preterm labor effectively.

Leptospira is belonged to phylum spirochaetes, which causes leptospirosis disease. Leptospirosis is a zoonotic disease with highly variable symptoms. The purpose of the study was to determine the serological incidence of Leptospira serovars among rice farmers in Veysian, Lorestan province.
200 rice farmers of Veysian were sampled (blood sample) clinically in 2014. Blood samples were transfered to the laboratory. The sera were transferred to -20° C until performance of MAT test. The serum samples were examined by the Microscopic Agglutination Test (MAT) method. The final dilution of leptospiral infection was determined by 1:200, 1:400 and 1:800 dilutions.
60 serum samples (30%) out of 200 samples were positive in 1:100 dilution. 38 (63.33%) L. grippotyphosa and 22 (36.67%) L.canicola antigens reacted positively . The infection rate was 65% for males and 35% for females. P value according to gender was 0.02. There is a significant correlation between leptospiral infection and gender based on statistical analysis. The highest and the lowest frequency of positive samples were related to age group over 50 and 21-30 years groups, respectively.
Leptospirosis is a common disease among rice farmers, and in Veysian according to the rice farms, and planting and harvesting which are in traditional way is introduced as an impotant infectious disease; therefore to prevent the spread of this disease, health and safty should be developed. Also, using mechanized methods of farming, planting and harvesting, leptospirosis can be prevented largely in the region.

Pseudomonas aeruginosa is an opportunistic pathogen and the cause of 10% to 15% of ýnosocomial infections.Virulence genes of Pseudomonas aeruginosa is one of the most ýaggressive mechanisms and the issue of medical opinion is important. The expression of many ýgenes is controlled and regulated in pathogenic bacteria Pseudomonas aeruginosa gene by a ýsystem called Quorum Sensing (QS). QS controls and regulates cell-to-cell communication ýsystem using small molecules in single-celled organisms SMs. This study was aimed at ýdefining the prevalence of QS genes in Pseudomonas aeruginosa isolated from human ýresources.ý
Initially 60 samples of Pseudomonas aeruginosa from human intestinal samples were prepared ýand confirmed by culture-specific diagnostic tests. Multiplex PCR test was ýperformed to detect genes. Antimicrobial susceptibility of the isolates against 10 antimicrobial agents was ýdetermined using standard disk diffusion method.ý
Multiplex PCR results showed that the frequency of the desired genes rhlR 5 %, lasR 48.3% and lasI 60%. The genes lasB, apr, rhlAB and rhlI were not detected in any of the samples. According to antibiogram, the most resistance was against amikacin, amoxicillin and cefotaxime and the most susceptibility was to ciprofloxacin and ceftazidime.
This study shows high prevalence of Quorom Sensing genes in Pseudomonas aeruginosa isolates of human origin.

Hepatitis C virus (HCV) is considered as one of the major pathogenic agents of chronic liver diseases. Previous studies have shown that HCV proteins can interaction with gene regulatory networks such as microRNAs. The aim of this study was to investigate the effect of HCV core protein on the expression of miR-150 in a cell culture model.
Plasmids expressing full HCV core protein was transfected into Huh7 cell lines while a GFP expressing plasmid employed as negative control. Subsequently, total RNA extracted and Real-Time PCR performed to measure the expression level of miR-150 expression. Moreover, trypan blue exclusion assay was performed to investigate the effect of core protein on cell viability.
The gene expression analysis of miR-150 in Huh7 cells showed that endogenous HCV core protein could significantly down regulation of miR-150 when compared to GFP control plasmid and normal cells (P Our study suggests that HCV core protein can led to down regulation of miR-150 expression. This data revealed that HCV protein interactions with cell regulatory machinery may contribute to pathogenesis of chronic liver diseases.

This study was done with the aim of investigating the role of cognitive and emotional deficiencies in anticipation of membership in addicted and non-addicted groups.
This fundamental and reviewing type research is a cross-sectional comparative study that was performed retrospectively. Population of the study was all the male substance abusers referred to addiction treatment centers in one of the cities of Lorestan province in 2014. The selected population included 100 of substance abusers and 100 normal people (from the patients, accompanies) selected by purposive sampling method. All participants completed cognitive failures questionnaire (CFQ) and alexithymia questionnaire (TSA-20). The point analysis was applied to analyze the data. Analysis was performed using SPSS-20.
In point analysis at simultaneous method, seven predicting variables (difficulty in describing and identifying feelings, thoughts turned to the outside, memory problems, distractibility, oversight and not reminding the names) and in the stepwise method, three predicting variables (cognitive failures, difficulty in describing feelings and memory problems) for the only function of the point is explained by the difference between two groups of addicted and non-addicted.
The results showed that addicts and non-addicts can be distinguished from cognitive and emotional impairment.

An increase in blood sugar levels after meals is the most common disorder in diabetes. Since bread is one of the main sources of food in Iran, we aimed to assesses the effect of five types of Iranian bread (Baguette, Lavash, Tafton, Sangak and Barley) on blood glucose level of type 2 diabetes patients and healthy subjects.
In this study, 150 participants including two equal groups of type 2 diabetic patients with diabetes and healthy controls were studied. Both groups of patients and controls randomly divided into five equal subgroups, and then each group received one of the five kinds of bread containing 50 g available carbohydrate. Blood glucose level was measured at baseline, 60 and 120 minutes after consumption of breads.
Results showed that the highest glycemic response was observed in blood sugar after ingestion of Baguette bread, in both groups. The variations of blood glucose after 120 min, in subjects who had received Sangak and Barley breads was significantly lower than those who consumed Baguette, Lavash and Tafton breads (P Sangak and Barley breads had more effec on blood glucose control, which can play an important role in the regulation of blood glucose levels in diabetic patients.

Given the role educational system, it is necessary to most desirable design and implements activities. Internal evaluation is process in which members of the department said the group's objectives and their performance are judged and then reviewed their role and for better performance, essential steps to take.The purpose of this study was the internal evaluation of Physiology Department of Lorestan University of Medical Sciences.
The study was descriptive and cross sectional conclucted in 2014-2015. Data was collected using questionnaire and was evaluated in 6 areas. Questionnaire was prepared and drafted by some faculty members and Medical Education Development Center. Based on the Likert scale, data was classified favorable, relatively favorable and unfavorable in a range of 0 to 5 points.
The results showed that the head of department area (acquired by averaging 4.23), faculty members (3.57), educational courses (3.96) and curriculums of the department of physiology (3.57) are favorable and areas of educational and research requirement and constructions (2.92) and research activities of the faculty members (2.73) are comparatively favorable.
According to Likert scale, department of physiology of Lorestan University of Medical Sciences was evaluated and ranked in all mentioned areas (acquired by averaging 3.39), therefore has a satisfactory level.

Toxoplasma gondii is one of the most common zoonotic parasites. The stray cats play an important role in the infecting intermediate hosts, due to easy access to raw meat and predation of infected rodents and birds and shedding oocyst on the environment. The aim of this study was to determine the prevalence of T. gondii antibody in the serum and oocyst shedding in the feces of stray cats and its relationship with some variables such as age, sex and inhabitant in Khorramabad, west of Iran
A total of 125 Stray cats trapped from different parts of city and were brought to the research laboratory to take blood and faces specimens. The blood samples of the cats (71 males and 54 females) were assayed for the prevalence of T. gondii using the IgG-ELISA, and their fecal samples collected through rectal swabs, and sugar floatation concentration method was applied for detection of oocyst.
From 125 cats, a total of 80 cats (64%) were positive for anti-Toxoplasma antibody, 42 cats (33.6%) were negative and 3 cats (2.4%) were in borderline. There was no significant difference in the T. gondii seropositivity between males and females, and also between cats living in different parts of city, but prevalence rate between different age groups were significant statistically (P The present study indicated a significant proportion of cats from Khorramabad, west of Iran. The T. gondii infection risk could be considerable if public health measures didnt take into account.

CD or gluten-sensitive enteropathy is caused by dietary gluten ingestion in geneticallysusceptible individuals.The aim of the study was to compare the current diagnostic methods of CD and relationship between these methods.
Material and In this study 50 patients suspicious to have celiac disease were studied. After IgA anti-TTG test using Eliza method, the patients went under upper endoscopy, then histopathologic findings were grouped by Marsh classification.
Fifty patients, 23 males and 27 females with mean age of 8.36 were included in the study. TTG-IgA test was positive in 45 patients. Most pattients were categorized as Marsh stage III ( 28 cases) by histopathologic examination, which can be seen in other studies. We found significant correlation between histopathologic and serologic findings (p-valu=0.014). no significant correlation was found between histopathological test and patients age.
Based on the results obtained in this study between histopathologic findings and serologic findings were significant relationship, The diagnostic approach presented in this study may also be useful in the assessment of CD. In the end, for a definitive diagnosis of celiac disease, molecular tests and also determination of haplotype HLADQ are recommended

The purpose of this study was to recognize the performance of the pectoralis major, anterior deltoid, and triceps muscles of the disabled male world and paralympic championsby the EMG.
The electrical activity of the pectoralis major, anterior deltoid, and triceps muscles of 24 disabled Iranian male world and paralympic throwers in sitting and standing positions was recorded by a surface electromyographic device. To determine the significant differences of the sitting and standing classes, the statistics techniques of the One Way ANOVA and the independent t- test at the 0.05 sinificant level were administered to the recorded data.
The activity (amplitude) of pectoralis major and anterior deltoid muscles of the participants differed significantly in the sitting classes. Also, the activity of triceps muscles in the standing classes and that of pectoralis major muscles of the sitting and standing classes while the amplitude of triceps muscles of sitting classes, pectoralis major and anterior deltoid muscles of the standing classes, and anterior deltoid and triceps muscles of both sitting and standing classes was not significantly different. (p The means of all the variables in the sitting classes were more than those in the standing classes. The highest amplitude belonged to the anterior deltoid, pectoralis major and triceps muscles of the sitting classes, respectively. This is due to the disabled throwers’ paralysis in the sitting position compared with that of the throwers in standing positions. The comparison of the amplitude recorded by surface electromyography of the disabled throwers’ muscles in all classes showed that the pectoralis major, anterior deltoid, and triceps muscles have major roles in the disabled male world and paralympic champions’ throwing events.