فهرست مطالب
Zahedan Journal of Research in Medical Sciences
Volume:19 Issue: 9, Sep 2017
- تاریخ انتشار: 1396/08/30
- تعداد عناوین: 5
-
-
Page 1BackgroundAndrogenetic alopecia is the main cause of hair loss and common baldness that affects psychological more than physiological aspects of peoples lives. Studies have shown that this multi factorial disorder is initiated by androgens secretion in pubertal period, minerals limitations, autoimmunity, mental stress, genetic predisposition and some alterations in hematological factors.ObjectivesThe aim of this study was to evaluate the involvement of hematologic parameters in this disease using a case control study design.MethodsIn this case-controlled study, two groups each of 80 individuals with androgenetic alopecia were voluntarily included in the study based on their medical histories and clinical examinations and subjected to blood tests for routine hematological parameters. The results were then compared and analyzed using SPSS version 16.0.ResultsOur findings indicated that all the parameters for both groups fall in normal ranges (Mean ± SD) but the values for RBC, HGB, MCH, MCHC, WBC, LYM and TIBC were significantly higher in patients than in normal group. The average counts of PLT was significantly lower in patients compared with the normal group. Otherwise, Persons tests for statistical correlations between two groups indicated that the pattern of correlations were abnormal in patients.ConclusionsOur findings indicated the presence of a chronic, immunologic and slowly progressing disorder that causes hair loss, the disease which is in turn triggered in pubertal period upon androgen secretion. We suggest, therefore, that the conditions may be ameliorated by prescription of iron tablet, platelet transfusion and anti-inflammation therapy.Keywords: Alopecia, Platelet Transfusion, Iron, Inflammation
-
Page 2BackgroundStroke can cause paralysis, muscle weakness, and loss of balance that may affect walking and routine activities.ObjectivesThe aim of this study was to evaluate the effect of ethyl alcohol extract of Matricaria chamomilla on cerebral ischemia-induced motor dysfunctions in rats.MethodsIn this experimental study, forty two male Wistar rats were divided into 6 groups consisting of control group, sham group, ischemia/reperfusion group and three treatment groups [treated with 50, 100, and 200 mg/kg doses of M. chamomilla extract and undergoing ischemia/reperfusion(I/R)]. Motor coordination and balance were evaluated using Rotarod test. Total antioxidant capacity, malondialdehyde (MDA), and nitric oxide (NO) levels of serum and brain were also determined.ResultsThe extract of M. chamomilla significantly improved I/R-induced motor dysfunction. Induction of I/R led to increase serum MDA, while the extract of M, chamomlla significantly reduced it. Administration all doses of M. chamomilla extract to the ischemic rats did not reduce the hippocampus MDA levels (P > 0.05). The extract of M. chamomilla at dose of 200 mg/kg slightly decreased cortex MDA (P > 0.01). It had no significant effects on the total antioxidant capacity of the brain (hippocampus and cortex) and serum. Injection of Matricaria chamomilla extract also did not change serum NO level.ConclusionsOur findings suggested that the Matricaria chamomilla extract could improve motor dysfunction.Keywords: Antioxidant Capacity, Malondialdehyde, Nitric Oxide, Matricaria chamomilla
-
Page 3BackgroundAutism spectrum disorder is a lifelong disorder and impairs function of people in different fields. Researchers assert that autism characteristics can be seen in the non-clinical population. One of problems which is common in this population is depression. When depression is coupled with an ASD, it can lead to a significant decrease of well-being and influence functioning. This research is aimed at studying the relationship between autistic characteristics and depression in male participants.MethodsThis cross-sectional study was conducted in Shahed University on male students. 180 questioners were distributed, but data of 120 students were appropriate to analysis. The subjects were assessed on the depression [BDI-II] and the autism-spectrum quotient [AQ]. Data were analyzed in SPSS-23 and AMOS.ResultsResults of SEM show that after controlling the measurement error and overlap among components of AQ, social skills [r = 0.20, PConclusionsBetter cognitive functioning may increase peoples awareness of their functional problems, especially in social situations, contributing to a negative self-image and emotional distress. The increased awareness of failure in the people with HFASD may lead to depression.Keywords: Depression, Broad Autism Phenotype, High Functioning Autism Spectrum Disorder
-
Page 4BackgroundProcrastination is common among students. There are inconsistent evidence indicating the relationship between anxiety and procrastination. Similarly, underlying mechanisms of this relationship is not fully understood. One of these mechanisms may be self-compassion that may counteracts the negative effects of anxiety and procrastination. Hence, this research is aimed at investigating the mediating role of self-compassion in the relationship between anxiety and procrastination.MethodsThis cross-sectional study was conducted in Shahed University. Subjects were selected from different faculties through cluster sampling method. Since a minimum sample size of 200 is necessary for Structural Equation Models, we distributed 300 questionnaires, but 210 questionnaires were appropriate to analysis. Students were asked to answer to tests, including anxiety, self-compassion, and procrastination scale.ResultsAnxiety is correlated with procrastination and all subscales of self-compassion. Three components of self-compassion, including self-judgment (r = 0.305, PConclusionsResults are consistent with the researches and theory. There are anxiety provoking factors among students correlated with the academic performance and getting accepted by peers, leading to self-judgment and over identification that are related to negative results such as procrastination.Keywords: Procrastination, Self, Compassion, Anxiety, Self, Judgment, Over, identification
-
Page 5BackgroundThe use of dietary supplements and drugs to improve performance and physical appearance has recently increased among professional and recreational ýathletes. Literature shows that bodybuilders, more than other athletes use supplements and drugs.ObjectivesThis study aims to predict the use of supplements and drugs by muscle dysmorphia and social physique anxiety variables among Hamedan bodybuilders.MethodsThis cross-sectional investigation was conducted with 438 bodybuilders in Hamedan province. For collecting data, we used a demographic questionnaire, muscle dysmorphia scale, and social ýphysique anxiety scale.ResultsThe results showed that 79.2% of the subjects used supplements, and vitamins (22.1%) and protein powders (21.9%) had the highest rates of use among supplements. Moreover, 145 subjects (33.1%) used drugs, and steroid derivatives (16.2%) and peptide hormones and growth factors (12.6%) had the highest rates of use among drugs. The results of t-test showed that muscle dysmorphia and social physique anxiety were significantly higher in the subjects who used supplements and drugs than those who did not. Additionally, the results of logistic regression indicated that muscle dysmorphia and social physique anxiety can predict the likelihood of drug abuse.ConclusionsThe present study provides novel findings of the effect of social physique anxiety and muscle ýdysmorphia on nutritional supplement and drugs use among bodybuilders. ýKeywords: Anabolic Steroids, Sports Supplement, Muscle Dysmorphia, Social Physique Anxiety