فهرست مطالب

Red Crescent Medical Journal - Volume:19 Issue: 11, Nov 2017

Iranian Red Crescent Medical Journal
Volume:19 Issue: 11, Nov 2017

  • تاریخ انتشار: 1396/09/30
  • تعداد عناوین: 18
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  • Yin Ying, Hongchun Li, Jiye Jin, Xuliang Lu, Pinpin Feng, Yunfeng Sun* Page 1
    Background
    Numerous studies have shown that long- term treatment with anticonvulsants may be an important risk factor for the onset of atherosclerosis, or worsening of its symptoms.
    Context: The present study aimed at investigating the relationship between carbamazepine (CBZ) monotherapy and plasma homocysteine (Hcy) levels in patients with epilepsy.
    Evidence Acquisition: Studies concerning homocysteine levels in carbamazepine monotherapy patients with epilepsy, which were published in VIP, Wanfang, CNKI, Cochrance Library, PubMed, Web of Science, and EMBASE, were included in March 2016. The quality of the controlled clinical trials (CCT) selected for this study was assessed using the Newcastle-Ottawa scale (NOS), and the relevant data of the included studies were extracted through RevMan5.2 software.
    Results
    In this meta-analysis, 22 eligible studies were enrolled including 9 Chinese and 13 English studies. The study included a total of 1604 cases including 575 cases of patient group and 1029 control group cases. Results of the meta-analysis showed that plasma homocysteine level in patients with epilepsy with long- term treatment of CBZ was significantly higher than that in the healthy control group [SMD = 1.55, 95% CI: [1.09, 2.01], P |Z|= 0.091 > 0.05 (no statistical significance), suggesting no significant publication bias in the study. Loss factor of safety (Nfs) 0.05 equaled 7269.16 (P = 0.05), meaning that addition of about 7269 negative results were required to overthrow the conclusion of this study.
    Conclusions
    The seizures significantly increased plasma homocysteine levels in the patients, thus it is appropriate to add folic acid, vitamin B12, and vitamin B6 to reduce the seizures. Moreover, homocysteine may be beneficial for those patients with epilepsy who take carbamazepine.
    Keywords: Epilepsy, Carbamazepine, Homocysteine, Meta, Analysis
  • Tahereh Yaghoubi, Ali Ardalan, Davoud Khorasani Zavareh *, Hamidreza Khankeh, Amir Nejati, Abass Ebadi Page 2
    Context: Disasters are increasing worldwide, with more devastating effects than ever before. Hospitals must maintain their normal functions or have an evacuation plan due to the rate of damages at the time of a sudden disaster. The present study was conducted to determine the effective determinants and components in hospital evacuation decision- making.
    Evidence Acquisition: In this systematic review study, which was conducted in 2016, bibliographies, citation databases, and other available records such as international guidelines, documents and reports of organizations and academic dissertations were used to find an answer to the following question: What are the effective components in hospital evacuation decision- making? Finally, 34 articles were included in this systematic review. This systematic review article was checked with PRISMA checklist.
    Results
    The common factors affecting hospital emergency evacuation decision-making were classified into 4 general categories and 40 subcategories, which have been explored during thematic analysis. These 4 categories included hospital infrastructure consequences, threat, internal factors, and external factors. Level of risk was the most important component of threat category and it was mentioned in most of the reviewed literature. Loss of electricity and water, communication and transportation, resources such as staff, and removing patient devices were the most mentioned factors in hospital infrastructure consequences, external factors, and internal factors, respectively.
    Conclusions
    Different variables affect the process of hospital emergency evacuation decision-making. Thus, further studies are needed to develop a decision-making tool for hospital emergency evacuations in Iran.
    Keywords: Hospital Evacuation, Decision, Making, Disasters, Emergencies
  • Aida Sarsarshahi, Maryam Ahmadi *, Zahra Niazkhani Page 3
    Context: Population aging is one of the most important health concerns worldwide, leading to an increase in the prevalence of chronic diseases such as dementia and Alzheimer disease (AD). Disease registries have great potential to determine the effect of clinical care, healthcare costs, and healthcare improvement for patients. Although there are several registries for dementia and AD worldwide, no systematic review is so far performed in this area. Therefore, the current study aimed at identifying the basic information in dementia and AD registries and comparing their characteristics.
    Evidence Acquisition: The current systematic review studied the dementia and AD registries in English literature based on keywords in the title with no time limitations, using the following databases: Institute of Electrical and Electronics Engineers (IEEE), ProQuest, PubMed, Science Direct, Web of Science, Scopus, Ovid Medline, Scientific Information Database (SID), and IranMedex (earliest entry to 07 February, 2017). In the current research, only the studies related to disease registries were evaluated.
    Results
    A total of 28 articles meeting the inclusion criteria were evaluated in the current study. Based on the findings, 22 dementia and AD registries were identified. The majority of the registries (13 registries) were from North America. In half of the registries, patient recruitment was performed among outpatients and inpatients referred to healthcare centers. The comparison of the structural information in these registry systems showed that they differed in terms of objectives, data sources, minimum data sets, and data quality.
    Conclusions
    The current study was the 1st systematic review of dementia and AD registries. Since there are no international standards to develop dementia and AD registries, comprehensive analysis can be effective to promote disease registry systems.
    Keywords: Dementia, Alzheimer Disease, Registries, Database
  • Mohammad Reza Yeganeh, Moluk Pouralizadeh*, Abbas Ebadi Page 4
    Background
    There are different tools for assessing evidence-based practice in nursing in Iran, however, there are some limitations in each of them, and they do not examine EBP comprehensively.
    Objectives
    The purpose of this study was to evaluate the validity and reliability of the Persian version of EBPQ.
    Methods
    This study was a methodological research on 300 nurses working in Guilan province (Iran). A cluster sampling was done. After a forward-backward translation, the questionnaire was translated into Persian and its psychometric evaluation was done.
    Results
    CVIs for all items were ≥ 0.8 and CVRs were ≥ 0.63. All of the impact scores were > 1.5. Cronbach’s alpha of the scale was 0.92. The ICC test was 0.96 and significant (P
    Conclusions
    This study introduces the evidence-based practice questionnaire (EBPQ) as a valid and reliable tool to assess the status of evidence-based practice among nurses in Iran.
    Keywords: Barriers, Nursing, Clinical Nurses, Evidence, Based Practice, Questionnaire
  • Vahideh Karimlou, Sakineh Mohammad Alizadeh Charandabi, Jamileh Malakouti, Mojgan Mirghafourvand * Page 5
    Background

    Attention to women’s health is considered a health priority in every country. One of the factors that promote women’s general health is self-efficacy.

    Objectives

    The present study was conducted to determine the effect of counseling on the self-efficacy of middle-aged women.

    Methods

    The present randomized controlled clinical trial was conducted on 102 middle-aged women (51 women in each group) and was covered by health centers in Tabriz in 2015 - 16. Participants were randomly assigned into two groups (one group received counseling and another did not) using the block randomization stratified based on age (40 to 50 and 50 to 60) in block sizes of 4 and 6. The intervention group received counseling on health promotion over three 45-minute sessions. Sherer et al’s general self-efficacy scale was completed in both groups before the intervention, and four and eight weeks after the intervention. Data were analyzed using independent t-test and repeated measures ANOVA.

    Results

    Before the intervention, no significant difference was observed between the two groups in terms of self-efficacy. Four and eight weeks after intervention, mean (SD) of self-efficacy scores were 69.0 (11.4) and 71.7 (11.1) respectively in the counseling group and 65.7 (13.2) and 64.9 (11.3) respectively in the control group. After the intervention, and with adjusting the baseline values, repeated measures ANOVA test showed a significantly higher mean self-efficacy score in the counseling group compared to the control group (Adjusted mean difference = 5.3; 95% confidence interval = 2.1 to 8.5; P

    Conclusions

    Counseling in middle-aged women can lead to improved self-efficacy, resulting in improved health in this age group.

    Keywords: Counseling, Self, Efficacy, Middle Aged, Women
  • Nader Parsa *, Samira Taravatmanesh, Maurizio Trevisan Page 6
    Background
    Contrary to popular belief, no study to date has provided evidence regarding the effect of low cholesterol level on extended overall survival.
    Objectives
    The aim of the current study was to examine the possible relationship between low serum cholesterol (
    Methods
    This observational, prospective, cohort study included 19 different large-scale dynamic cohort studies in Italian populations, followed-up for 9 years. The Cox proportional hazard ratio (HR) was measured to analyze the data. The associations were presented as HRs with 95% confidence intervals.
    Results
    The results showed that 1906 deaths (males, 1439 and females, 467; total non-CVD, 1214 and total CVD, 692) occurred during the 9-year follow-up. Total mortality for non-CVD was almost twice (1.76) higher than that of CVD. There was a significant inverse association between low serum cholesterol and non-CVD mortality in males, unlike females. The association of low cholesterol level with non-CVD mortality was more significant than CVD mortality among males (non-CVD: HR, 2.06; 95% CI, 1.54 - 2.74 vs. CVD: HR, 0.81; 95% CI, 0.54 - 1.22). However, an insignificant association was found between both non-CVD and CVD mortalities and low serum cholesterol among females (non-CVD: HR, 1.52; 95% CI, 0.91 - 2.50 vs. CVD: HR, 1.56; 95% CI, 0.72 - 3.38).
    Conclusions
    The findings indicated an inverse association between low serum cholesterol and high non-CVD mortality versus CVD mortality. Therefore, non-CVD mortality rate was higher than CVD mortality in males and lower in females at minimum cholesterol level.
    Keywords: Mortality, Noncardiovascular Disease, Cardiovascular Disease, Low Serum Cholesterol
  • Fatemeh Abbaszadeh, Nahid Sarafraz, Mahboobeh Kafaei Atrian *, Zohreh Sadat, Azam Bagheri, Alireza Moravveji Page 7
    Background
    Identifying the best marker for appropriate screening of risk factors of chronic diseases seems necessary in any society.
    Objectives
    This study aimed at performing a comparative evaluation of anthropometric indices to determine a better marker for prediction of high blood pressure in adolescents.
    Methods
    This cross-sectional study was done during 2013 on 1046 students, aged 11 to 19 year old in Kashan, who were chosen by cluster and class sampling method. Height, waist circumference (WC), waist-to-hip ratio (WHR), waist-to-high ratio (WHtR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) of the subjects were measured. Blood pressure of all subjects, who had their blood pressures measured during the first visit, was measured during the second and third visit again, and the three measured blood pressure averages was considered as subject's blood pressure.
    Results
    This study showed a significant positive correlation between BP and body mass index (BMI), WC, WHR, and WHtR indices (P
    Conclusions
    The WHtR, as a relatively simple, inexpensive, and convenient measurement method is the best anthropometric index for determination of blood pressure in these subjects.
    Keywords: Hypertension, Adolescent, Body Mass Index, Waist Circumference, Waist, to, Hip Ratio, Waist, to, High Ratio
  • Ali Vafaei Najar, Hadi Tehrani, Hossein Imamian, Hamidreza Mohades Hakak, Mohammad Vahedian-Shahroodi * Page 8
    Background
    Diabetes could be especially difficult for females. The burden of diabetes on females is unique because the disease could affect both mothers and their unborn children.
    Objectives
    The aim of this study was to determine the effect of developing a communication network among physicians on the level of HbA1C and Fasting Blood Sugar (FBS) in patients with diabetes in Iran.
    Methods
    This study was a randomized clinical trial performed with 100 patients, who were randomly divided to experimental and control groups. The study was conducted from 20/11/2015 to 15/1/2016. A communication network was established among the physicians at health centers, to which patients in the intervention group were referred. The data were collected using a checklist of demographic information of patients. Laboratory results regarding the level of Glycated Hemoglobin (HbA1C) and Fasting Blood Sugar (FBS) of patients were gathered at baseline and 4 months after the establishment of the communication network.
    Results
    After the development of the communication network, HbA1C levels had reduced from 8.14 ± 2.08 to 7.90 ± 2.01 in the intervention group (P
    Conclusions
    The results showed that for successful control of diabetes, physicians need to communicate with each other and share information and experiences. Furthermore, establishing a communication network among physicians could be effective to control diabetes.
    Keywords: Type 2 Diabetes_Communication_Hemoglobin A1C
  • Sedigheh Farzi, Alireza Irajpour *, Mahmoud Saghaei, Hamid Ravaghi Page 9
    Background
    The goal of healthcare professionals is to provide safe care, prevent injury, and promote the health of patients. Different factors and conditions, in particular, medication errors, may threaten patient safety.
    Objectives
    This study was conducted to explore and to describe the role of interactions among healthcare professionals regarding medication errors in intensive care units.
    Methods
    The study was conducted using a descriptive qualitative method in 2016. The participants were purposively chosen. Data were collected by semi-structured interviews and used qualitative content analysis for the analysis. The setting of the study included 16 internal, surgical, poisoning, and cardiac intensive care units of 7 educational hospitals affiliated to Isfahan University of Medical Sciences located in central Iran with a total of 190 beds. Participants included 19 members of the healthcare team (physician, nurse and clinical pharmacist) with at least 1 year of work experience in intensive care units.
    Results
    The main category and 3 sub- categories were extracted from interviews. The 3 sub- categories were: “weak interprofessional interaction (physician and nurse)”, “weak intraprofessional interaction (among physicians)”, and “weak interaction of physician as well as nurse with the patient and family”.
    Conclusions
    The findings suggest that medication errors may occur due to lack of interprofessional collaboration and weak communication of the healthcare team with the patient and his family. The collaboration between healthcare providers and communication with patients directly had an impact on patient outcomes. To improve the quality and safety of care delivery, healthcare center managers need to promote interprofessional collaboration, the participation of patient and family in care plan, interprofessional development, and implementation of programs to prevent as well as reduce medication errors in intensive care units.
    Keywords: Patient Safety, Medication Errors, Intensive Care Units, Communication, Nurse, Physician, Qualitative Research
  • Maliheh Deldadeh Arani, Mohsen Taghadosi *, Hamid Reza Gilasi Page 10
    Background
    Hypertension is a major health problem in all communities that is closely associated with lifestyle. Different educational models have been used to improve the lifestyle in these patients. However, inconsistent results have been reported.
    Objectives
    This study aimed to investigate the effect of education based on the BASNEF model on lifestyle in patients with essential hypertension.
    Methods
    This single-blind randomized controlled clinical trial was conducted in 2015 on 80 patients with essential hypertension. The intervention group received five sessions of training based on the BASNEF model, while the control group received routine care. A two-part instrument was used in this study. The first part included a demographic questionnaire and the second part comprised the life style questionnaire (LSQ). The LSQ was responded in two times, i.e. before and one month after the intervention. Descriptive statistics, independent sample t-test, and analysis of covariance were used to analyze the data.
    Results
    The mean score of lifestyle in the intervention group was 121.80 at the start of the study that changed to 149.60 (with an increase of 27.8) after the intervention (P
    Conclusions
    Using a training program based on the BASNEF model was effective in improving the lifestyle in patients with hypertension. Thus, this model of behavior modification can be used as an inexpensive and applicable method in modification of lifestyle and behavior change in patients with hypertension.
    Keywords: Hypertension, Life Style, Patient Education
  • Neda Izadi, Sayed-Saeed Hashemi-Nazari, Elaheh Rafiee, Azam Malekifar, Farid Najafi Page 11
    Background
    Overweight/obesity is increasing in both developing and developed countries. Its socioeconomic determinants have been well studied in developed countries. It has been reported that the family socioeconomic status is associated with overweight/obesity in childhood and adolescence. However, socioeconomic inequality has not been studied sufficiently in developing countries.
    Objectives
    This study aimed to determine the status of socioeconomic inequality in overweight/obese high school students and its related factors in Kermanshah, Iran.
    Methods
    Within a cross-sectional study and using stratified cluster random sampling, 1440 students in the academic year of 2015 - 16 were selected from all high schools in Kermanshah, Iran. To collect data, we used a demographic, socioeconomic status, and nutritional status questionnaire. Height and weight of the participants were measured and the status of obesity was determined by calculating body mass index (BMI). The concentration index and a concentration curve were used for the measurement of inequality. We used multinomial logistic regression to investigate the factors associated with obesity. The collected data were analyzed using Stata 11 software.
    Results
    The mean age of 1445 students participating in the study was 16.35 ± 0.84 years. Of all, 51.63% (746 students) were female and the rest were male. The median of BMI was 20.54 kg/m2 (IQR = 4.32) in female participants, 21.20 (IQR = 4.42) in male participants, and 20.76 kg/m2 (IQR = 4.49) in all the participants. Concerning asset index, Concentration Index for overweight/obesity was 0.09 in girls (95% CI: -0.14 - 0.33), -0.02 in boys (95% CI: -0.14 - 0.09), and 0.01 in the entire participants (95% CI: -0.13 - 0.17). The odds of overweight/obesity in males was 1.81 times higher than that in females; the odds of overweight/obesity in those consuming high-fat food was 1.61 times higher than that of people not consuming high-fat diet.
    Conclusions
    Overweight/obesity is more prevalent in adolescents with low socioeconomic level; this indicates the shift of the problem to the poorer groups of the community. Predominance of boys and the use of high-fat foods are affecting obesity/overweight; therefore, it must be considered in all health policy interventions.
    Keywords: Socioeconomic Inequality, Overweight, Obesity, Adolescents, Concentration Index
  • Maryam Saghafi-Asl, Mehranghiz Ebrahimi-Mameghani * Page 12
    Background
    Chronic low-grade inflammation has been confirmed to be a major etiological factor in polycystic ovarian syndrome (PCOS). The anti-inflammatory effects of quercetin, a major flavonol in onion, have been suggested by experimental studies. However, lack of data exists to investigate the effects of onion on inflammatory markers in PCOS.
    Objectives
    This study aimed at assessing the effects of raw red onion consumption on inflammatory markers in PCOS.
    Methods
    Fifty-four overweight/obese patients with PCOS were randomly assigned to either High-Onion (HO; raw red onions: 2 (40 - 50 g/day) for overweight and 2 (50 - 60 g/day) for obese patients) or Low-Onion (LO; raw red onions: 2 (10 - 15 g/day)) group over 8 weeks in this randomized controlled trial (RCT). Serum adiponectin, leptin, and high-sensitivity C-reactive protein (hs-CRP) levels and their correlations with metabolic and anthropometric parameters were assessed at baseline and endpoint.
    Results
    The 2-month treatment with onion could not significantly effect mean serum levels of adiponectin, leptin, or hs-CRP. However, the percentage change of serum adiponectin was significantly different between the two groups after 8 weeks (-11.9% in LO vs. 48.32% in HO; P = 0.026). Percentage change of serum leptin and hs-CRP showed no significant differences between the 2 groups. Leptin had significant correlations with most anthropometric and metabolic variables of insulin resistance (P
    Conclusions
    The 8-week intervention with red onion could increase percentage changes of serum adiponectin level in overweight/obese females with PCOS. However, no such effect was observed for serum leptin as well as hs-CRP levels.
    Keywords: Polycystic Ovary Syndrome, Inflammation, Adiponectin, Leptin, CRP, Onion, Quercetin
  • Hasan Abolghasem Gorji, Noureddin Niknam, Nahid Aghaei *, Tahereh Yaghoubi Page 13
    Background
    An increase in disasters around the world like bioterrorism attacks emphasizes the need to assess healthcare workers’ preparedness to respond to bioterrorism. Nurses form the majority of first responders in disasters and emergencies, thus it is important to guarantee that their knowledge and skills are adequate to respond to such events.
    Objectives
    This study aimed at assessing the level of nurse’s knowledge and attitude of Sari city of Mazandaran province about bioterrorism, in 2015.
    Methods
    Overall, 240 nurses participated in this cross-sectional study that was conducted at the University of Mazandaran Medical Sciences. The units were selected through the accessible sampling method. Data were collected by a questionnaire in 3 sections, demographic data, knowledge, and attitude, respectively.
    Results and
    Conclusions
    The results showed that 91.7% of samples had low knowledge about bioterrorism and 93.3% had no opinion in regarding attitude of bioterrorism. Little knowledge of nurses regarding bioterrorism attacks indicates inefficiencies in hospitals units. Therefore, bioterrorism preparedness should be proposed through continuing education for under graduate and post-graduate nursing curriculum.
    Keywords: Bioterrorism, Knowledge, Attitude, Nurses
  • Elaheh Tekieh, Mohammad Hassan Nikbin, Hedayat Sahraei, Mostafa Ghaneyi, Masoomeh Kazemi *, Hamed Aliyari Page 14
    Background
    Human beings firmly obtain a better understanding of the creator, its aims and destination, natural phenomena as well as the surrounding concepts with the help of thoughts. Invitation towards contemplation is one of the principles of Holy Quran’s teachings. Thought is one of the best activities of the human being’s brain from the neuroscience point of view, which occurs in specific parts of the cerebral cortex. These areas consist of parts of the cerebral cortex, which either does not exist in other creatures or is not highly developed.
    Objectives
    The purpose of this study was to investigate the importance of thought from the Holy Quran’s point of view and the Foundations of Neuroscience.
    Methods
    This research was carried out during year 2015 in the city of Tehran (the capital city of Iran). In this qualitative study, data were collected based on the Holy Quran and the interpretation of authentic books of the Quran and matching interpretation of these verses with neuroscience articles and books in the field of thought.
    Results
    Careful consideration of the data led to the identification of 18 verses of the Holy Quran that pointed directly to thinking, which were consistent with accepted principles in neuroscience.
    Conclusions
    Scientific secrets of the Holy Quran can be easily revealed by making a connection between a medical sciences, basic sciences, and Quranic sciences. There is hope of greater connection between the community of researchers in different fields with Quranic scientists, which might lead to the discovery of the secrets of this scripture and deep realization of the mystery of permanence.
    Keywords: Central Nerves System, Holy Quran, Prefrontal Cortex, Sense Training, Thought
  • Atefeh Fakharian, Shahram Kharabian Masouleh *, Saba Karimzadeh, Hamidreza Jamaati Page 15
    Background
    Noninvasive positive-pressure ventilation (NIPPV) has been safely used in selected patient populations. The purpose of this study was to determine the safety and efficacy of NIPPV outside the intensive care unit (ICU) in a tertiary hospital. This descriptive, cross sectional study was performed at Masih Daneshvari Hospital, Tehran, Iran during 2011 - 2015.
    Methods
    Between March 2011 and June 2015, patients requiring NIPPV were enrolled in the study. The study population included all eligible patients. Census sampling was applied in this study. The patients’ medical history (including comorbidities), age, sex, and hospital ward in which NIPPV was delivered were assessed retrospectively. Moreover, venous pH, partial pressure of carbon dioxide (PCO2), and bicarbonate (HCO3-) were analyzed before and after the intervention (NIPPV application).
    Results
    A total of 946 patients, including 598 (63.2%) men and 348 (36.8%) women, received NIPPV for inpatient hospital care. The mean age of the patients was 61.92 ± 15.5 years (range, 3 - 102 years). Indications for NIPPV included exacerbation of chronic obstructive pulmonary disease (COPD; 55.4%), obstructive sleep apnea (OSA; 6%), bronchiectasis (7.8%), concurrence of COPD and OSA (4.8%), neuromuscular disorders (1.7%), congestive heart failure (4%), postthoracotomy pain (0.6%), thoracic malignancy (2.1%), pulmonary thromboembolism (1.1%), pneumonia (7.3%), asthma (1.5%), interstitial lung disease (2.5%), tuberculosis (4%), and cystic fibrosis (1.3%). We found significant improvements in venous pH and PCO2 with no significant changes in HCO3- (P > 0.05).
    Conclusions
    NIPPV could be safely used under the supervision of trained pulmonologists in non-ICU settings. This method was effective in treating acute abnormalities in venous blood gas, including pH and PCO2.
    Keywords: Noninvasive Positive, Pressure Ventilation, Safety, Efficacy, COPD, OSA, CHF, Venous Blood Gas
  • Seyyed Mohammad Miri, Seyed-Moayed Alavian* Page 16
    Breakdowns of the 7-year war in Syria, especially in the health care infrastructures, such as water networks, and in the basic health requirements, such as public hospitals, emergency equipment from one side and emigration of the skilled resources from the country from the other side, has led to a disaster not only for the residents and neighboring countries but also for all other countries, which accept asylum seekers. Deficiency of national immunization programs and safe water has increased the risk of new epidemics of enterally transmitted virus infections like Hepatitis A virus (HAV) infection. Ringing alarms of a public health emergency must concern all authorized policy makers around the world. Vaccination against HAV, both for residents and asylum seekers, controlling the immune system of all other nations involved in Syria, fixing the water networks, and investing on infrastructures of the primary hygiene requirements would eliminate the risk of communicable infections in all the region.
    Keywords: Hepatitis A Virus_Epidemiology_War_Asylum Seeker_Syria
  • Mehdi Fazlalipour, Behzad Mohsenpour, Vahid Baniasadi, Tahmineh Jalali, Tahereh Mohammadi, Sanam Azad-Manjiri, Yasaman Jamshidi, Sara Azizizadeh, Motahareh Hosseini, Sahar Khakifirouz, Mostafa Salehi-Vaziri * Page 17
    Introduction
    Crimean-Congo hemorrhagic fever (CCHF) is a fatal tick-borne viral zoonosis. CCHF virus (CCHFV) has 7 distinct genotypes with a determined geographical distribution pattern. However, similar genotypes have been reported from distant geographical areas.
    Case Presentation
    On 4 June 2016, a CCHF suspected case from Sanandaj city, Kurdistan province of Iran, was confirmed with CCHFV infection by RT-PCR test. The phylogenetic analyses showed a strain belonging to Europe-1 genotype.
    Conclusions
    Considering the similarity of Iranian strain of Europe-1 genotype to the strains from Turkey and Russia, it could be claimed that Europe-1 genotype has introduced to Iran from European countries. However, to have a better understanding about the circulation of CCHFV Europe-1 genotype in Iran, further investigations should be performed.
    Keywords: Crimean, Congo Hemorrhagic Fever Virus, Sequence Analysis, Iran
  • Fereshteh Nouri, Arman Zargaran, Mohsen Naseri * Page 18