Asian Journal of Sports Medicine
Volume:6 Issue: 3, Sep 2015

Cisplatin (CP) is a chemotherapy drug and nephrotoxicity is considered as its major side effect. Aerobic exercise is well known as an approach to reduce the side effects of many drugs.. This study was designed to determine the protective role of aerobic exercise against CP-induced nephrotoxicity.. Thirty male Wistar rats were randomly divided into four groups. Group I had aerobic exercise on a treadmill one hour per day and five days per week for eight weeks. Then, the exercise protocol was continued for another week, but during this week, the animals also received CP (2.5 mg/kg/day; ip). Group II underwent the same protocol as group I without exercise in the last week during the CP therapy. Groups III and IV were assigned as positive and negative control groups, and were treated with CP and saline without exercise, respectively. Finally, the animals were sacrificed for the biochemical measurement and tissue histopathology investigation.. CP alone without exercise increased serum levels of blood urea nitrogen (BUN), creatinine (Cr), and malondialdehyde (MDA); and kidney nitrite level, while treadmill exercise in group I significantly ameliorated these parameters (P < 0.05). Kidney and serum levels of MDA and nitrite did not alter significantly. Also, the severity of kidney tissue damage decreased significantly in groups I and II (P < 0.05).. Aerobic exercise may reduce CP-induced nephrotoxicity with a favorable effect on renal function by increasing activation of antioxidant system..

Musculoskeletal pain is a common problem among athletes. Apart from sport injuries, the myofascial pain syndrome is another important problem that affects performance of the athlete.. The aim of this study was to evaluate the effects of therapeutic sequences of the hot pack in combination with ultrasound on the physiological responses over the latent myofascial trigger point (LMTrP) of upper trapezius muscle.. Thirty subjects with a latent myofascial trigger point (LMTrP) in both sides of the upper trapezius muscle participated in the study (age 27.33 ± 4.34 years, weight 58.11 ± 7.47 kg, height 161.50 ± 5.82 cm, pressure pain threshold 2.28 ± 0.24 kg/cm2, pain intensity 7.17 ± 2.25 VAS). All subjects received both treatments (hot pack followed by ultrasound: HP + US; and ultrasound followed by hot pack: US + HP) by randomization with a 24 to 48-hour interval between sessions. Outcome measures, including the tissue blood flow (TBF), pressure pain threshold (PPT), supra-thermal threshold (STT) and visual analog scale (VAS) were evaluated at baseline, immediately, after 30 minutes and after 60 minutes.. The TBF and PPT significantly increased from baseline in both treatment conditions (i.e. HP + US and US + HP), while the HP + US condition showed a trend toward significant difference in VAS and STT in 45°C.. The application of HP and US treatment induces physiological responses (especially, TBF and PPT) on the LMTrP. This finding provides the direction toward the management of MTrPs condition..

Glycogen depletion and hypoglycemia have been associated with fatigue and decrement of performance during prolonged exercise. This study investigated the effectiveness of Acacia honey drink as a post-exercise recovery aid on glucose metabolism and subsequent running performance in the heat..Patients and Ten subjects participated in this randomized cross-over study. All subjects performed 2 trials. In each trial, all subjects went through a glycogen depletion phase (Run-1), 2-hour rehydration phase and time trial running phase (Run-2). In Run-1, subjects were required to run on a treadmill at 65% VO2max in the heat (31°C, 70% relative humidity) for 60 min. During 2-hour rehydration phase, subjects drank either plain water (PW) or honey drink (HD) with amount equivalent to 150% of body weight loss in 3 boluses (60%, 50% and 40% subsequently) at 0, 30 and 60 min. In Run-2, the longest distance covered in 20 min was recorded for determining running performance. Two-way repeated measured ANOVA and paired t-test were used for analysis.. Running distance in Run-2 covered by the subjects in the honey drink HD trial (3420 ± 350 m) was significantly (P < 0.01) longer compared to plain water PW trial (3120 ± 340 m). In general, plasma glucose, serum insulin and osmolality were significantly (P < 0.05) higher in HD compared to PW during the rehydration phase and Run-2.. These findings indicate that rehydration with honey drink improves running performance and glucose metabolism compared to plain water in the heat. Thus, honey drink can be recommended for rehydration purpose for athletes who compete in the heat..

Fencers often complain of progressive difficulty in breathing during matches, which is generally attributed to restricted air, light and heat circulation from wearing a mask. Physiologically, the nasal structure generates airflow resistance that can reach -50% of the total respiratory resistance..

This study aims to investigate the presence of nasal obstruction in fencers and the relationship with the use of mask..

An observational study on 40 fencers (18 males, 22 females) was conducted. Fencers perform a usual assault, wearing the mask and standardized physical exercises (running, sprints and obstacles) without the mask. ENT examination with a nasal flexible fiberscope, Anterior Active Rhinomanometry (AAR) and Peak Nasal Inspiratory Flow (PNIF) measurement before and after physical activity with or without the mask was recorded..

Before physical exercise, the total nasal airway resistance mean value for AAR was 0.33 ± 0.17 Pa/cm3/s at 150 Pa. After a match with the mask, the mean value was 0.28 ± 0.16 Pa/cm3/s. After normal physical exercises without mask, the mean value was 0.24 ± 0.15 Pa/cm3/s. Using t tests, statistically significant difference between nasal resistance before and after physical activity (P < 0.05) was observed, but no significant difference in nasal resistance between the basal value and that taken after a match wearing the masks (P = 0.1265). PNIF values significantly increase with exercise (P < 0.05)..

Our study shows that wearing the mask causes increased breathing impairment in fencers, when compared with similar physical activity without the mask..

We express the detection of the prohibited substance prednisone, prednisolone in player’s urine sample by long and intensive use eye steroid drops.. In a rare case in Iranian football, a player’s urine sample had corticosteroids. After all investigations, it was demonstrated that systemic effects can be induced by using long-term of ophthalmic prednisone.. It seems to be required to investigate the systemic effects on long term and excessive use of topical corticosteroid drops can have on the result of the sample analysis and showing positive results..

Buttock pain is a relatively common complaint among adolescent athletes and can have a very broad differential diagnosis.. The authors present a previously unreported case of acute obturator internus and obturator externus strain in an adolescent male American football player. The diagnosis was made by MRI. The patient was treated with relative rest, physical therapy, and gradual return to physical activities as tolerated.. Despite rarity of the hip external rotator muscles strains, it should be considered in the differential diagnosis of athletes with proximal posterior thigh and buttock pain..

It has been reported that high intensity long term training in elite athletes may increase risk of immune function.. This study is to examine training effects on immunoglobulin and changes of physiological stress and physical fitness level induced by increased cold stress during 12-week winter off-season training in elite Judoists..Patients and Twenty-nine male participants (20 ± 1 years) were assigned to only Judo training (CG, n = 9), resistance training combined with Judo training (RJ, n = 10), and interval training combined with Judo training (IJ, n = 10). Blood samples collected at rest, immediately after all-out exercise, and 30-minute recovery period were analyzed for testing IgA, IgG, and IgM, albumin and catecholamine levels.. VO2max and anaerobic mean power in IJ (P < 0.05) and anaerobic power in RJ (P < 0.05) were significantly increased after 12-week training compared to CG. There was no significant interaction effect (group × period) in albumin after 12-week training; however, there was a significant interaction effect (group × period) in epinephrine after 12-week training (F (4, 52) = 3.216, P = 0.002) and immediately after all-out exercise and at 30-minute recovery (F (2, 26) = 14.564, P = 0.008). There was significantly higher changes in epinephrine of RJ compared to IJ at 30-minute recovery (P = 0.045). There was a significant interaction effect (group × period) in norepinephrine after 12-week training (F (4, 52) = 8.141, P < 0.0001), at rest and immediately after all-out exercise (F (2, 26) = 9.570, P = 0.001), and immediately after all-out exercise and at 30-minute recovery (F (2, 26) = 8.862, P = 0.001).. Winter off-season training of IJ increased physical fitness level as well as physical stress induced by overtraining. Along with increased physical stress, all groups showed reduced trend of IgA; however, there was no group difference based on different training methods..

The peaking period for endurance competition is characterized for a relative increase of the intensity of training, after a longer period of training relatively dominated by lower intensity and higher volume. The present study was designed to compare physiological and 10 km performance effects of high intensity training (HIT) versus race pace interval training (RP) during peaking for competition in well-trained runners..Patients and 13 athletes took part in the study, they were divided into two groups: HIT and RP. HIT performed short intervals at ~105% of the maximal aerobic velocity (MAV), while RP trained longer intervals at a speed of ~90% of the MAV (a speed approximating 10 km race pace). After 12 weeks of baseline training, the athletes trained for 6 weeks under one of the two peaking regimes. Subjects performed 10 km prior to and after the intervention period. The total load of training was matched between groups during the treatment phase. Subjects completed a graded treadmill running test until volitional exhaustion prior to each 10 km race. MAV was determined as the minimal velocity eliciting maximal oxygen consumption (VO2max).. Both groups significantly improved their 10 km time (35 minutes 29 seconds ± 1 minutes 41 seconds vs 34 minutes 53 seconds ± 1 minutes 55 seconds, P < 0.01 for HIT; 35 minutes 27 seconds ± 1 minutes 40 seconds vs 34 minutes 53 seconds ± 1 minutes 18 seconds P < 0.01 for RP). VO2max increased after HIT (69 ± 3.6 vs 71.5 ± 4.2 ml.Kg-1.min-1, P < 0.05); while it didn’t for RP (68.4 ± 6 vs 69.8 ± 3 ml.Kg-1.min-1, p>0.05). In contrast, running economy decreased significantly after HIT (210 ± 6 ml.Kg-1.km-1 vs 218 ± 9, P < 0.05).. A 6 week period of training at either 105% of MAV or 90% of MAV yielded similar performance gains in a 10km race performed at ~90% MAV. Therefore, the physiological impact of HIT training seems to be positive for VO2max but negative for running economy..

Sedentary behavior, which includes sitting and TV viewing, has been identified as an independent risk factor for type 2 diabetes and cardiovascular disease. Breaking sedentary behavior improves metabolic health such as postprandial glycaemia and insulinemia. However, the mechanisms underlying this effect are unclear.. Here, we examined whether breaking sitting by standing and acute exercise reduces postprandial oxidative stress..Patient and Fifteen participants performed 3 trials (sitting, standing, and exercise), each lasting 2 days, in a randomised order. On day one of sitting trial, participants sat in a chair. For the standing trial, the participants stood 6 times, for a 45-minute period each time. For the exercise trial, the participants walked or ran at approximately 60% of age-predicted maximum heart rate for 30 minutes. On day two of each trial, participants rested and consumed the standardised breakfast and lunch. Blood samples were collected in the morning and afternoon on day one, and fasting and at 2, 4, and 6 hours postprandially on day two.. The concentrations of serum derivatives of reactive oxygen metabolites (d-ROMs) measured at 4 hours (P = 0.064) and 6 hours (P = 0.071) tended to be higher than that in the fasting state in the sitting trial, but not standing and exercise trial (two-factor analysis of variance (ANOVA), trial × time interaction, P = 0.006).. Our results indicate the importance of reducing sitting time for improving postprandial oxidative stress status..

In 2009, the International Judo Federation (IJF) created a World Ranking List (WRL) to classify athletes according to their performance in international-level competitions and to qualify athletes for the Olympic Games.. Considering that this ranking system provides useful information concerning athletes’ performance in competitions during a 2-year period and during Olympic Games, the objective of this paper was to verify how long- and short-term performances in WRL competitions predict the performance in the 2012 London Olympic Games..Patients and Data from 233 male and 154 female athletes who took part in the London Olympic Games were analyzed considering: measures of long- and short-term performance, as well as measures of athlete approach to the Olympic Games and the points obtained in the 2012 London Olympic Games. Athletes were divided into male and female groups. Stepwise linear regression was conducted to predict points acquired in the Olympic Games. Significance level was set at 5% for all analyses.. The equation found for females was: 46.055 + 0.142 (points valid in the two years period) - 14.422 (number of competitions in 2012) (adjusted R2 = 0.240, standard error = 130 points, P < 0.05). For males, the equation found was: -38.079 + 0.102 (points valid in the two years period) + 1.088 (percentage of matches won in 2012) (adjusted R2 = 0.257, standard error = 109 points, P < 0.05).. Thus, only 24% to 26% of female and male judo performance in the 2012 London Olympics could be predicted, respectively, by variables derived from the IJF WRL..

The role of the autonomic nervous system (ANS) in the cardiovascular regulation is of primal importance. Since it has been associated with adverse conditions such as cardiac arrhythmias, sudden death, sleep disorders, hypertension and obesity.. The present study aimed to investigate the impact of recreational football practice on the autonomic cardiac function of male children, as measured by heart rate variability..Patients and Forty-seven male children aged 9 - 12 years were selected according to their engagement with football oriented practice outside school context. The children were divided into a football group (FG; n = 22) and a control group (CG; n = 25). The FG had regular football practices, with 2 weekly training sessions and occasional weekend matches. The CG was not engaged with any physical activity other than complementary school-based physical education classes. Data from physical activity, physical fitness, and heart rate variability measured in time and frequency domains were obtained.. The anthropometric and body composition characteristics were similar in both groups (P > 0.05). The groups were also similar in time spent daily on moderate-to-vigorous physical activities (FG vs. CG: 114 ± 64 vs. 87 ± 55 minutes; P > 0.05). However, the FG performed better (P < 0.05) in Yo-Yo intermittent endurance test (1394 ± 558 vs. 778 ± 408 m) and 15-m sprint test (3.06 ± 0.17 vs. 3.20 ± 0.23 s). Also, the FG presented enhanced autonomic function. Significant differences were detected (P < 0.05) between groups for low frequency normalized units (38.0 ± 15.2 vs. 47.3 ± 14.2 n.u (normalized units)), high frequency normalized units (62.1 ± 15.2 vs. 52.8 ± 14.2 n.u.), and LF:HF ratio (0.7 ± 0.4 vs. 1.1 ± 0.6 ms2).. Children engaged with regular football practice presented enhanced physical fitness and autonomic function, by increasing vagal tone at rest..

The article highlights an athlete’s cognitive appraisals form the onset to return to play. The narrative provides how an athlete constructs a sense of self within personal and situational factors and describes the subjective experiences during rehabilitation. The study examined the cognitive appraisal and psychological response within the backdrop of personal and situational factors in an injured athlete..Patients and The study is contextualized within the injury rehabilitation experiences of a cycling national athlete aged about 18 years old who was presented with the complaint of right shoulder pain, following a right shoulder dislocation. The 22 page narrative account provided by the athlete offered a holistic and integrated account of his experiences from the onset to return to play. A six step narrative analysis was analyzed by two qualified psychologists and two medical practitioners.. The themes are extracted to understand what was important to the participant. The cognitive appraisal and lived experiences are discussed within three dominant themes: 1) Injury and consequences in sporting life. 2) Childhood experiences, emotions, social support. 3) Trusting relationship, behavioral outcome and hopeful future. The study indicates the influence of personal and situational factors in cognitive appraisals leading to emotional and behavioral responses during rehabilitation.. The study demonstrates how individual experiences become a dynamic core of psychological response during injury rehabilitation. The study highlights the cognitive appraisals and, emotional upheaval to provide an understanding of how personal and situational factors affect the psychological responses of an injured athlete. Findings suggest the need to develop a holistic approach as an effective strategy in injury rehabilitation..

Karate is one the most popular combat sports in the world. Physical fitness assessment on a regular manner is important for monitoring the effectiveness of the training program and the readiness of karatekas to compete.. The aim of this research was to examine the criterion related to validity of the karate specific aerobic test (KSAT) as an indicator of aerobic level of karate practitioners..Patients and Cardiorespiratory responses, aerobic performance level through both treadmill laboratory test and YoYo intermittent recovery test level 1 (YoYoIRTL1) as well as time to exhaustion in the KSAT test (TE’KSAT) were determined in a total of fifteen healthy international karatekas (i.e. karate practitioners) (means ± SD: age: 22.2 ± 4.3 years; height: 176.4 ± 7.5 cm; body mass: 70.3 ± 9.7 kg and body fat: 13.2 ± 6%).. Peak heart rate obtained from KSAT represented ~99% of maximal heart rate registered during the treadmill test showing that KSAT imposes high physiological demands. There was no significant correlation between KSAT’s TE and relative (mL/min kg) treadmill maximal oxygen uptake (r = 0.14; P = 0.69; [small]). On the other hand, there was a significant relationship between KSAT’s TE and the velocity associated with VO2max (vVO2max) (r = 0.67; P = 0.03; [large]) as well as the velocity at VO2 corresponding to the second ventilatory threshold (vVO2 VAT) (r = 0.64; P = 0.04; [large]). Moreover, significant relationship was found between TE’s KSAT and both the total distance covered and parameters of intermittent endurance measured through YoYoIRTL1.. The KSAT has not proved to have indirect criterion related validity as no significant correlations have been found between TE’s KSAT and treadmill VO2max. Nevertheless, as correlated to other aerobic fitness variables, KSAT can be considered as an indicator of karate specific endurance. The establishment of the criterion related validity of the KSAT requires further investigation..

The five-kilometer time trial (TT5km) has been used to assess aerobic endurance performance without further investigation of its validity.. This study aimed to perform a preliminary validation of the TT5km to rank well-trained cyclists based on aerobic endurance fitness and assess changes of the aerobic endurance performance.. After the incremental test, 20 cyclists (age = 31.3 ± 7.9 years; body mass index = 22.7 ± 1.5 kg/m2; maximal aerobic power = 360.5 ± 49.5 W) performed the TT5km twice, collecting performance (time to complete, absolute and relative power output, average speed) and physiological responses (heart rate and electromyography activity). The validation criteria were pacing strategy, absolute and relative reliability, validity, and sensitivity. Sensitivity index was obtained from the ratio between the smallest worthwhile change and typical error.. The TT5km showed high absolute (coefficient of variation < 3%) and relative (intraclass coefficient correlation > 0.95) reliability of performance variables, whereas it presented low reliability of physiological responses. The TT5km performance variables were highly correlated with the aerobic endurance indices obtained from incremental test (r > 0.70). These variables showed adequate sensitivity index (> 1).. TT5km is a valid test to rank the aerobic endurance fitness of well-trained cyclists and to differentiate changes on aerobic endurance performance. Coaches can detect performance changes through either absolute (± 17.7 W) or relative power output (± 0.3 W.kg-1), the time to complete the test (± 13.4 s) and the average speed (± 1.0 km.h-1). Furthermore, TT5km performance can also be used to rank the athletes according to their aerobic endurance fitness..

Cytokines play an important role in modulating the muscle’s metabolic and immunological responses to exercise.. In the present study, we investigated changes in the serum levels of Interleukin (IL)-15 as well as tumor necrosis factor (TNF)-α and high sensitivity C-reactive protein (hs-CRP), as markers of inflammation, in athlete and non-athlete young men following eccentric (ECC) and concentric (CON) emphasized resistance exercise (RE)..Patients and This study recruited 28 young males, 14 athletes and 14 non-athletes. Subjects completed two bouts of ECC and CON emphasized RE five days apart. Each bout included seven exercises that emphasized all major muscle groups with weight loads of 70% - 80% of one repetition maximum (1RM) for CON RE and 90% - 100% of 1RM for ECC RE. We analyzed subjects’ blood samples before and immediately after each bout of exercise to determine cytokine and hs-CRP serum levels according to enzyme-linked immunosorbent assay.. Statistical analysis showed a significant difference between IL-15 serum levels before and after ECC and CON RE in non-athletes (P = 0.03). In athletes, IL-15 serum level only increased after ECC RE (P = 0.01), which was noted to be the highest degree of change in IL-15 levels in all subjects. For athletes, the hs-CRP levels significantly decreased (P < 0.05). The serum levels of both TNF-α and hs-CRP were also significantly down-regulated after ECC RE in non-athletes.. These results indicated that fitness level and RE could modulate circulating levels of IL-15 and suggest the potential anti-inflammatory effects of IL-15 during RE..