مجله علوم پزشکی پارس
سال دهم شماره 1 (پیاپی 19، بهار 1391)

Oxidative damage is one of the major factors that lead to cell damage, organ dysfunction and mortality in sepsis. Thus, an attractive candidate for pharmacologic treatment of the septic syndrome is deferoxamine (DFX), an antioxidant iron chelator used for the removal of iron and a potential free radical scavenger. In this study, the impact of DFX administration on the survival of septic animals was evaluated. Sepsis was induced in 20 rats, using the Cecal Ligation and Puncture method (CLP) and 10 rats randomly received subcutaneous DFX (total dose: 40mg/kg) twice and the other 10 rats received placebo (normal saline). All the rats had equal health status, environment and nutrition. The time of the death of the rats was recorded. Deferoxamine increased the survival period in rats and the difference was statistically significant. Treatment with DFX significantly increases the survival of septic rats.

Depression and low self-esteem are the most important psychological disorders common among adolescents. But few studies have investigated the association between parental bonding patterns and depression and low self esteem in adolescents. The aim of this study was to detect the effects of parental bonding on depression and self esteem during adolescence in Bushehr in 2010. In this cross-sectional study, a total of 482 adolescents (246 females and 236 males) in the first grade at 8 high schools of Bushehr were selected according to cluster random sampling. A series of valid and reliable questionnaire by each subject including the Beck Depression Inventory, Cooper Smith Self esteem Inventory and Parental Bonding Inventory (PBI) were completed. Descriptive statistics and independent t-test were used for analysis of the data in SPSS, version 11.5. Parental care was more associated with depression and low self esteem in both male and female adolescents than parental protection. An interactive combination of low care and high protection (affectionless control) revealed a significant relationship with depression and low self esteem in female adolescents. The results showed that a combination of low care and over-protection increases the risk of depression and low self esteem in female adolescents. Optimum parental behavior is characterized by the behavior through which adolescents get a feeling of freedom, love and protection.

Introduction and Pseudomonas aeruginosa is a key opportunistic pathogen causing severe acute and chronic nosocomial infections in immunocompromised or catheterized patients. It is prevalent in burn wound infections and it is generally multi-drug resistant. This study evaluated antimicrobial activity of ZnO and catechin and EDTA on the most common pathogen bacteria Pseudomonas aeroginusa by standard microdilution test depend on NCCLS. Zinc acetate dehydrate and Ethilen glycol (EG) were dissolved in 50 ml Distilled water with 10/1 ratio (Zn/EG). The solution were heated at 80 0C until little the gel of zinc acetate was obtained. Then gel was dried in the oven for 12h. Dried gel is calcinated at 300 0C for 24h Size and type of these Nanoparticles was characterized by scanning electron microscopy (SEM) and X-Ray-: Diffraction (XRD). pseudomonas aeroginusa strain (ATCC 27853) were cultured on nutrient agar medium (NA) for 24h at 370C. The microbial Suspension (1×106 cells/ml) was prepared. Minimum Inhibitory Concentration (MIC) test for ZnO and EDTA and Catechin were evaluated by microdilution test. Evaluation of Morphology and measurement of the size of the ZnO showed that nanoparticles were spherical with 30- 90 nm diameter. MIC of ZnO and EDTA and Catechin on pseudomonas aeroginusa was respectively 0.0003, 24.92 and 7.24 µg/ml. In this study we synthesized the ZnO nanoparticles with chemical method and we found that it has antimicrobial activity in low concentration compared with Catechin and EDTA. We offered that catechin and ZnO nanoparticles are good candidate for eliminating some contamination including of Pseudomonas aeroginusa in medical industrial.

Iran is one of the endemic countries of brucellosis. The prevalence of this disease in Iran is about 225 in 1000000. In this study the authors wanted to evaluate the demographic characteristics and wright test titers in patients who had treated with diagnosis of brucellosis. Methods and Materials: In this descriptive cross sectional study; the dossier of 168 patients with brucellosis between 2005 and 2008 has been evaluated. Mean of the age of the studied patients was 28.51 ± 17.07 years and the most of the patients were in 10-29 year group. 68.5% of the patients were male and 31.5% were female. Most of the patients (60.1%) were rancher; and wright titer was 1/320 in 33.1% of the cases. Ranchers and the individuals with 10 – 29 years old are the groups with the most risk for brucellosis. Men are more in risk than women. It is better to dilute the serum of the patients up to 1/320 in standard tube agglutination test.

Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo. A total of 71 women with type II diabetes were randomly assigned to a group that administered Omega-3 capsules or control group. First, the study subjects filled in a questionnaire including age, height, weight, waist circumference, and hip circumference. In addition, blood samples were taken to do the blood tests. In the second step, the intervention was done for 8 weeks and then data on the aforementioned variables were collected. In the blood samples visfatin and lipid profiles (LDL: low density lipoprotein, HDL: high density lipoprotein, TG: triglyceride and cholesterol), glucose, and HbA1c were measured. There was no significant difference in serum visfatin level between groups before the intervention (p=0.14). However, after the intervention, the mean serum visfatin level in the Omega-3 group was significantly (P<0.001) higher. In addition, the mean differences before and after the serum visfatin level showed a significant difference in both groups (P<0.001). The use of omega-3 can increase visfatin level and also improve the effect of insulin in patients with type 2 diabetes. According to the similar effects of insulin and visfatin, the use of Omega-3 by diabetic patients is recommended. Also, further studies are recommended to be conducted on his subject to confirm the results of this study.

Introduction; The purpose of this study was to examine the effect of 3 Vibration, PNF(Proprioceptive Neuromuscular Facilitation) and Mixture stretching method on flexibility of hamstring muscles in non-athletics male students. Method; for this purpose 30 students were selected by goal oriented method and then were divided to 3 groups: vibration (N=10), PNF (N=10) and mixture (N=10). Firstly, the flexibility of hamstring muscles was measured by the “passive leg straight test”, then every 3 group were performed their trains for 4 weeks and After ending training passive leg straight test in 3 groups was attained. The results indicated that the flexibility in every 3 groups significantly increased after training protocol (p = 0.001). Although, in hamstring muscles flexibility was not found the significant difference between vibration and PNF groups(p > 0.05), its value in mixture group was significantly more than other groups(p = 0.000). Thus based on results of this study, although the athletics achieve relatively favorable levels by each of vibration or PNF methods, the combining these methods can be help to improvement and developing in flexibility up to most value. Hence, this stretch training method advice mostly in the sports such as gymnastic, wrestling and dancing that were needed to high flexibility.

One of the methods of breast cancer screening is its self-examination. This study reviews the effect of education about breast self-examination on women’s knowledge, attitude and practice. This clinical trial was conducted on 100 (50 cases, 50 controls) women who referred to health centers in NourAbadMamasani. The participants in the experimental group were trained during 3 sessions. The data gathering tool was a questionnaire consisting of four parts: personal details, and questions on knowledge, attitude and practice. The collected data were analyzed in SPSS software using T-test, ANOVA, Regression and Chi square. The results of the study showed that education increased the women's awareness, attitude and performance of breast self-examination. The mean scores of awareness, attitude and performance significantly increased after the educational intervention in the experimental group (p=/001) as compared to the control group (p=0.309, p=0.233, p=0.489). There is a need that health care centers provide some educational courses on prevention and treatment of breast cancer for women in the appropriate time.

child behavior problems is reflecting psychological problems for parents, especially mothers, and mental illness of one parent likely increases to have mental illness in the children. Considering the negative interaction between parent and child diseases, this study aimed to assess the relationship between child behavior problems and maternal mental health was conducted. This study was done on 80 mothers of solidarity with children with behavioral problems referred to the pediatric clinic psychiatric ward, Golestan Hospital, Ahwaz city and the easy way to go based on successive selection was performed. Research tool, contains a mental health questionnaire (SCL-90- R) and children's behavioral problems questionnaires (CBCL). For data analysis was used from Pearson correlation and regression analysis. The results show that among all children with behavioral problems has a significant positive relationship with all subscales of maternal mental health. There is a significant positive relationship between external behavioral problems of children with all subscales of maternal mental health. significant positive relationship was obtained between internal behavioral problems of children with all subscales of mental health of mothers except the individual sensitivity. Considering the high correlation between child behavior problems and maternal mental disorder, it is necessary for reducing effects of psychological problems of mothers on children to ponder design.

Despite the fact that cervical cancer is highly preventable, it still continues to occur, even among women who have access to cancer screening and treatment services. This study aimed to determine the effect of health education program based on Health Belief Model on the performance pap smear test. This random clinical trial was carried out on 120 women in Zarandieh. Data were collected using a valid and reliable questionnaire based on Health Belief Model which was completed by the participants. After the analysis of pre-test results, the educational program was designed and the experimental group participated in 3 educational sessions during one week. Two months after the intervention, a post-test was performed and analyzed using t-test، t-paired and x2. Our findings indicated that mean scores of HBM Model constructs (self-efficacy, susceptibility, severity, benefit and barriers perceived) were significantly increased in the experimental group compared to the controls after the intervention. Also, performance of pap smear test increased significantly among the experimental group as compared to the controls after the intervention (P<0. 01) (before intervention 30%, after intervention 53. 9% in the experimental group). Health education programs are recommended to use the theories and models of changing of individual's behavior in organization levels for to Help Plan Effective Programs as the uptake of cervical cancer screening (Pap smear).