Jentashapir Journal of Cellular and Molecular Biology
Volume:9 Issue: 6, Dec 2018

The aim of this study was to investigate the psychometric properties of Rusbult’s relationship investment scale based on the main components’ analysis, through varimax rotation, and obtaining a precise instrument for Iranian samples. The statistical population of this study consisted of all 1416 married students of Qazvin Payame Noor University in the academic year of 1396 to 1397, from which 302 subjects were selected by convenience sampling. The statistical population consisted of 300 Payame Noor University students in Qazvin, who were selected by convenience sampling. Overall 176 of the cases were female and the rest were male. The results obtained from the main components’ analysis using varimax rotation based on four factors converged with the English version of relationship investment scale and only some subscales needed to be modified as follows: Satisfaction (including questions 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 21, 22, 23, 24, and 25), alternative relationships (including questions 26, 27, 28, 29, 30, 31, 32, 35, 36, and 37), investment (including questions 16, 17, 18, 19, 20, 33, and 34), and commitment (including questions 11, 12, 13, 14, and 15). The results of this study revealed that Rusbult’s relationship investment scale is a suitable instrument to assess the quality of relationship between couples in Iran’s society and since one of the effective variables in sustaining marital life is couples’ investment in this relationship, Rusbult’s relationship investment scale is an appropriate instrument to achieve this goal

From the past and till now, infectious intestinal parasites have been widely distributed across the world. Parasitic diseases are a major health-economic concern in developing countries. The high prevalence of parasitic infections is mostly related to issues such as poor personal hygiene, unhealthy water supplies, and lack of health education. Due to geographic location and diverse climate conditions, Iran has a variety of human and animal parasites. In this study, the prevalence of intestinal parasites was reported in the samples collected from the Central Laboratory of Borujen, Iran. The sampling method was a survey sampling from all individuals referred to the Central Laboratory of Borujen. All of the stool specimens were prepared through a direct method (phylogenetic serum) and examined by light microscopy. Among positive cases, 42 (53.8%) were male and 36 (46.2%) were female, thus there was no significant correlation between the prevalence of infection and sex. The highest level of contamination was for Giardia lamblia to the extent of 75 cases (96.1%), two cases of Enterobius vermicularis (2.6%) and one case of Blastocystis hominis (1.3%). Out of the total number of positive cases, 76 cases (97.4%) infected with protozoa and 2 cases (2.6%) with helminths. The findings of this study showed that due to the good level of hygiene in addition to cold and dry weather of Borujen, the frequency of intestinal parasites in this city has been low. However, similar to other parts of the country, the most prevalence of contamination was related to young ages and Giardia

Obstructive uropathy disease is a potentially lethal disease caused by the urination disorder, which is of great importance to proper treatment.

Based on the mentioned section, the aim was to compare the results and complications of percutaneous nephrostomy with hemodialysis in correcting water and electrolyte disorders in patients with obstructive uropathy.

In this as a clinical trial study, thirty patients with obstructive uropathy were considered as the study group. Patients were randomly divided into hemodialysis and PCN (percutaneous nephrostomy) groups. In both groups, BUN/Cr, Na, and K were measured every six hours. The variables T1 (time to preparation for action), T2 (time to clearance), T3 (total hospitalization time), pain score, satisfaction rate, and complications in both groups were compared. Finally, the data were analyzed using the SPSS software.

Results show that T1 in both PCN and hemodialysis groups was not significantly different. However, T2 and T3 in the PCN group had a significant decrease compared to the hemodialysis group, also the satisfaction rate in patients with PCN was better than hemodialysis. Concentration of potassium and creatinine in the PCN method decreased more than hemodialysis. However, there was no significant difference in the trend of reduction of other indicators such as sodium concentration, systolic, and diastolic blood pressure in both methods.

PCN can be an alternative, appropriate, cheap, and less complicated method for patients with obstructive uropathy.

The aim of this study was to determine the equivocal HER2 gene expression in patients with invasive ductal carcinoma of the breast approved by the chromogenic in situ hybridization (CISH) or fluorescence in situ hybridization (FISH) method and its association with clinicopathologic variables.

This cross-sectional census-based study was conducted with information obtained by filling out questionnaires based on patient records or telephone contacts. Referring to the pathology lab archive, we extracted all immunohistochemistry (IHC) results related to the patients of breast cancer with HER2 2+ between 2011 and 2016. The patients’ information and the results of the CISH or FISH method were obtained, as well.

The mean age of 247 patients was 48.21 ± 11.33 years. The result of the complementary CISH or FISH test was negative in 124 (50.2%) patients and positive in 123 (49.8%) patients. There was a significant relationship between the age groups and CISH (P value < 0.05). In the age group of fewer than 29 years, there was the most likelihood of CISH positivity and in the age group of 60, there was the most likelihood of CISH negativity. There was a significant relationship between KI-67 status and CISH result. Our results revealed that false negative HER2 test was high.

this result may be due to the type of the kit or antibody used or different guidelines used for the interpretation of the test. It is proposed to perform more precise complementary tests to determine the status of this gene. Moreover, laboratories should follow the ASCO/CAP guideline for HER2 evaluation in breast carcinoma.