فصلنامه طب مکمل
سال چهارم شماره 1 (پیاپی 10، بهار 1393)

Previous studies have revealed that doing exercise plays an important role in anxiety reduction. Due to the high rate of anxiety in diabetic patients، the present study has been designed with the aim to investigate the effects of Pilates exercises on anxiety reduction in patients with of diabetes type II. In this clinical trial study، 70 women suffering from diabetes type 2 were randomly divided into an experimental group (35 patients) and a control group (35 patients). The instrument of data collection was a demographic questionnaire and Spilberger questionnaire. First، the rate of anxiety in both groups was measured before the intervention. Then، certain modified Pilates exercises were carried out in the experimental group twice a week over a period of 8 weeks. During the same period، the control group received conventional medications (Glibenclamide and Metphormin tablets and a diabetic diet). Afterwards، anxiety in both groups was measured again. Finally، the collected data were analyzed through SPSS 17. 0 software and descriptive statistics، paired t-test and co-variance test in the level of p≤0. 05. The mean rate of anxiety before and after intervention in the experimental group were 6. 67 ± 8. 86 and 50 ± 7. 65. respectively with a statistically significant difference (p=0. 001) Eta Squared indicates that Pilates exercises can reduce anxiety in the experimental group by 32. 4 percent comparing with the control group. Findings of the present study reveals that Pilates exercises help reduce anxiety in patients with diabetes and can be used as a complementary treatment.

Dysmenorrhea is one of the most common disorders in women، of which 60-93% of women suffer. The treatment of this disorder all over the world is using pain-killers، consuming herbal medicines and massage therapy. The aim of this study is to investigate the effects of Stachys Lavandulifolia on pain relief in women with primary dysmenorrhea. The present study is a clinical research which has been conducted with the aim to investigate the effects of Stachys Lavandulifolia in menstrual pain relief in female students of Toyserkan Azad University being randomly selected. The students were randomly divided into control and experimental groups; each containing 45 students. Initially، the participants of intervention and control groups were requested to drink Stachys Lavandulifolia and placebo respectively at a dose of 10 gram، 3 times a day at the interval of 2 days before and 3 days after the menstruation period; continuing for 3 months. The results were registered before the intervention and 1& 3 months after the intervention. The pain measurement instrument in this research was Visual Analog Scale. Independent t-test and X2 were utilized in order to analyze the collected data. The findings showed a meaningful difference regarding pain severity in intervention group after 1 & 3 months of Stachys Lavandulifolia consumption comparing with control group (p=0/001); as the pain reduced after Stachys lavandulifolia consumption. The results of the present study revealed that Stachys Lavandulifolia is effective in reducing menstruation pain and can be a fine alternative to chemical medicines and their side-effects.

Sleep disorders and intermittent hypoxia leads to an increase in the development of cardiovascular complications. Aromatherapy brings about the release of endorphins in the brain resulting a feeling of well-being. Citrus Aurantium is known as a relaxant plant and sleep booster. The aim of the present study is to determine the scented effects of “Citrus Aurantium” on the sleep quality of the patients suffering from cardiovascular diseases. This research is a clinical trial with a control group with Pre- and post-test. The patients hospitalized in Coronary Care Units were randomly divided into control and intervention groups based on the entrance criteria. A romatherapy has been carried out through using the essence of “Citrus Aurantium” 10%، and placebo carried out for three successive nights. In order to check the last night’s sleep quality out، especially in terms of the pre-and post-sleep effects، the Hospital Sleep Questionnaire was filled out in both trial groups. The collected data were analyzed by SPSS 20 software، Chi 2 Correlation Test، U Mann–Whitney، T-test، and Wilcoxon signed-rank test was interpreted as well. Participants were divided into two 30-person group having no background meaningful differences (p > 0. 05). The effect of Aromatherapy by the use of Citrus aurantium essence on the quality of hospital sleep was meaningful through using statistic measurements. The sleep quality had a meaningful difference between the two groups in case of the patient’s last night’s sleep condition، the number of times the patient would get out of bed during the night and the time needed to go back to sleep again (p<0/05). However، it had a meaningful effect on the initiating time to sleep، the sleep longevity and sleep again after a period of being awake. Aromatherapy by the use of essence of Citrus aurantium can be used as a helpful remedy for sleep disorders in heart patients.

Considering the painfulness of labor، the present study was performed aimed to investigate the effect of Citrus Aurantium aroma on the level of pain in the active phase of first labor. The present research has been done as a clinical trial study on 126 nulliparous women (63 subjects in intervention group and 63 subjects in control group) admitted to Valie-Asr hospital in Toyserkan. In aromatherapy group 4ml essence of Citrus Aurantium impregnated gauze، and in the control group، only 4ml normal saline impregnated gauze were attached to their dress collar، and the administration was repeated every 30 minutes. The pain severity was measured at the beginning of the study in both groups and in dilatations 3-4، 5-7، and 8-10cm phase after intervention. Participants were followed up until the delivery time. The data were collected through demographic and obstetric questionnaire، observation checklist، and pain numerical rating scale. The data were then analyzed through using independent t-test، Man Withny-u and chi square. The mean pain severity score after the intervention in intervention group in dilatation 3-4 cm (4. 97± 0. 74)، 5-7 cm (6. 65± 0. 48) and 8-10cm (7. 57± 0. 56) decreased significantly (P=0. 001) compared with control group in dilatation 3-4 cm (8. 08± 0. 67)، 5-7 cm (8. 67 ±0. 56) and 8-10 cm (9. 46± 0. 53) The findings of the study revealed that aromatherapy of Citrus aurantium essence alleviates the labor pain; therefore، this method is recommended to reduce the labor pain.

Due to the importance of Rifampin on Tuberculosis treatment and the high prevalence of brucellosis and tuberculosis in Iran، it is necessary to replace Rifampin in brucellosis treatment with other drugs that are better tolerated and have fewer side effects. This research is a double-blinded clinical trial in which 36 patients were in group 1 prescribed by doxycycline capsule and garlic tablet for 8 weeks plus gentamicin for one week and 36 patients were enrolled as group 2 being prescribed by doxycycline and rifampin for 8 weeks plus gentamicin for one week. The data were collected and analyzed by SPSS version18. The mean age was 40. 2±17. 1 in group 1 and 40. 1±15. 9 in group 2. Treatment failore was 8. 8% in group 1 and 7. 8% in group 2. There was no significant difference in rate between two groups (P=0. 62). The disease recurrence after 9 months was 14. 7% in group 1 and 8. 6% in group 2 (p=0. 42). Due to the same effect of garlic and Rifampin in this study and in order to prevent rifampin resistance in tuberculosis patients and its less side effects، it is recommended to replace garlic as an alternative drug in brucellosis treatment.

The aim of the present study is to evaluate the effect of alcoholic extract of Chelidonium majus concentration of cholesterol and thyroid hormone levels in the male rats having hypercholesterolemia. In this study، 40 male Wistar rats were divided into five groups of control group (n=8) with normal diet، observing group with fat dietary، and three experimental groups receiving the same fat diet plus ethanol extract of the Chelidonium majus plant of 100، 200، 300 (mg/kg). After this period (21 days) blood samples were collected and after measuring the amount of thyroid hormones of T3، T4، TSH and also the amount of cholesterol، the data were analyzed by using SPSS software، ANOVA and t-test. There was a significant increase in the amount of cholesterol، T3 a nd T4 serum level in observation group comparing with control group (P<0. 05) and the amount of T3 a nd T4 in groups receiving the maximum dose of Chelidonium majus extract had the minimum decrease comparing to the group receiving moderate dose (P<0. 05). The results demonstrate that Chelidonium majus alcoholic extract can reduce the concentrations of thyroid hormones and the amount of cholesterol and increase the amount of thyroid-stimulating hormones as well، which is probably due to the existence of plant’s alkaloids and flavonoids، as well as the negative feedback mechanism of thyroid hormones.