فصلنامه فیزیولوژی ورزشی
پیاپی 15 (پاییز 1391)

Abstract The purpose of this study was to investigate the relationship between resting visfatin levels and visfatin changes during endurance exercise with aerobic fitness and body composition. For this purpose, forty six subjects (Mean±SD; age, 42.8±16.0 y; height, 171.7±5.4 cm; weight, 73.6±9.7 kg) participated in this study. In one session after determining body composition characteristics including weight, WHR and BMI, maximal oxygen consumption (Vo2max) was determined after 5 minutes warm-up by using a progressive exercise test on a cycle ergometer. After one week all subjects performed an acute endurance exercise at 60% of Vo2max for 30 minutes on a bicycle. Two blood samples were taken before and immediately after exercise and were analyzed for visfatin and glucose concentrations. To determine the correlations among the variables Pearson’s correlation was used. Results showed no significant correlations between serum visfatin with aerobic fitness (r=0.17, P>0.05) and body composition parameters (P>0.05). However, changes in visfatin during endurance exercise were positively and significantly correlated with aerobic fitness (r=0.349, P=0.018) and glucose (r=0.363, P=0.013). In addition, data analysis revealed that aerobic fitness is negatively and significantly correlated with resting glucose and glucose changes during exercise (P<0.05). Based on the results of the present study it could be concluded that aerobic fitness has no relationship with resting serum visfatin, though the higher aerobic fitness might result in more changes in visfatin responses to exercise, which might be an indicator of visfatin rules in improving the aerobic performance through NAD+ and increases in insulin during and immediately after exercise. Key words: Endurance exercise, Vo2max, NAMPT, BMI, WHR

The comparative study of effects the two types of aerobic continues endurance and interrupted training on HSP70 levels in Mice with breast cancer tumor. The purpose of this study was to compare effects of the two types of aerobic continues endurance and interrupted training on levels of HSP70 in mice with breast cancer tumor. For this reason 30 female balb/c mice were utilize and after transplant carcinoma tumor to mice randomly divided in 3 groups as fallow:1-tumor-contriol, 2:endurance training-tumor,3:interval training-tumor. endurance continues training protocol was done for 6 weeks at 25% to 75% vo2max and interrupted training protocol was done for 6 weeks at 20% to 55%vot2 max between 1 until 10 interval rep *1 min. Blood samples were collected after protocol and Eliza method used for measuring. Data were analyzed by using repeated measure of ANOVA followed by Tuky test at p<0/05 The result of this study showed rate of HSP70 in interrupted group decreased and in endurance continues training increased but there were no significant difference between groups. Also data analyze showed tumor volume in interrupted group decreased significant and in endurance continues group increased significant. based on the result of this research; doing interrupted exercise with change the rate of HSP70 can is effective in improving cancer treatment as a supplement in addition to other treatments.The comparative study of effects the two types of aerobic continues endurance and interrupted training on HSP70 levels in Mice with breast cancer tumor. The purpose of this study was to compare effects of the two types of aerobic continues endurance and interrupted training on levels of HSP70 in mice with breast cancer tumor. For this reason 30 female balb/c mice were utilize and after transplant carcinoma tumor to mice randomly divided in 3 groups as fallow:1-tumor-contriol, 2:endurance training-tumor,3:interval training-tumor. endurance continues training protocol was done for 6 weeks at 25% to 75% vo2max and interrupted training protocol was done for 6 weeks at 20% to 55%vot2 max between 1 until 10 interval rep *1 min. Blood samples were collected after protocol and Eliza method used for measuring. Data were analyzed by using repeated measure of ANOVA followed by Tuky test at p<0/05 The result of this study showed rate of HSP70 in interrupted group decreased and in endurance continues training increased but there were no significant difference between groups. Also data analyze showed tumor volume in interrupted group decreased significant and in endurance continues group increased significant. based on the result of this research; doing interrupted exercise with change the rate of HSP70 can is effective in improving cancer treatment as a supplement in addition to other treatments.