The Effect of Synthesis Conditions on Morphology and Size of Silica Nanostructures Particles

The aim of the present research was to optimize practical conditions of the sol-gel synthesis of silica nanoparticles. In so doing, silica particles were synthesized using sol-gel method and their size and morphology were investigated by use of SEM and TEM images. The effect of changing the mole ratio of reactive comparents, acids and silica pre-matter, acid type and different silica pre-matter used on morphology and the size of products was investigated by using SEM and TEM. The reaction time was studied as a very important factor in products’ digestion phase which plays a significant role in determining particles’ size and rate of cracking products. Finally, optimized conditions to produce 50-80 nm diameter nanostructures silica were reported. These products can be used as drug delivery systems.