The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats

The purpose of this study was to investigate the effects of three sessions of running on a negative slope (eccentric contraction) on changes of the serum levels of aspartate aminotransferase (AST) and alanin aminotransferaze (ALT) in adult male rats. 20 adult male rats were divided randomly into two equal groups (exercise and control). Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training. Exercise increased the levels of serum AST and ALT enzymes, significantly (p<0.05). Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver.