Relation between Serum Parathormon Hormone (PTH) and Serum Zinc Levels in Hemodialysis Patients

Secondary hyperparathyroidism is a common and curable complication in CRF patients. Although secondary hyperparathyroidism and zinc deficiency both are seen in CRF patients as complication but correlation between them is not well defined. In this study we have evaluated the correlation between serum zinc levels and serum PTH in hemodialysis patients.

This cross-sectional study was performed on one group consisting of hemodialysis patients (30 cases)، in Mashhad Imam Reza hospital. Patients who were under regular hemodialysis for at least 3 months after starting dialysis، with minimum age of 15، and were stable in the last 2 months entered the study. Levels of zinc، calcium، phosphorus، PTH، albumin and ALP were measured. Serum zinc was measured in fasting status by spectrophotometery.

Prevalence of zinc deficiency in hemodialysis patients was 65%. In hemodialysis patients no significant correlation was detected between serum zinc and PTH. There was also no significant correlation between serum zinc and calcium، phosphorus، ALP and albumin. However in hemodialysis patients there was a significant correlation between serum albumin and PTH.

In hemodialysis patients there was no significant correlation between serum zinc levels and serum PTH.