Effect of Arnebia euchroma root extract on burn wound healing in Balb/c mice

One of the major causes of mortality and disability in the world is burning. The proper treatment of burns has been considered by physicians from past to present. Properties of medicine plants in burn wound healing have been proven in various studies. Arnebia euchroma is a rich source of antioxidants. This study was carried out to investigate the effect of Arnebia euchroma on second-degree burn wound healing in Balb/C. In this experimental study، 105 Balb/C male mice (5 groups of 20 equal mice and 1 group with 5 mice) weighing 20gr were studied. Mice in 5 groups with Vaseline 1 gr، Silver sulfadiazine 1 gr، without intervention، Arnebia euchroma 1%، and 10% were treated topically for 21 days two times per day. Wound size and healing percentage at day 0، 7، 14 and 21 were measured. Data were analyzed using Kruskal-Wallis and Dunn''s post hoc statistical tests. Results showed that the most recovery was observed in Silver groups، without intervention، Vaseline، Arnebia euchroma 1%، and Arnebia euchroma 10%، respectively. Silver group showed the best healing effects between other study groups (P<. 0. 05). This study shows that Arnebia euchroma root did not have any effect on healing of second degree burn wounds in Balb/C. More study was recommended for evaluating the effects of other dose and extracts of the plant on burn healing.