Comparison of serum level of CRP and platelet in acute perforated and non- perforated appendicitis in Imam Hossein hospital of Shahroud in 2011

Appendicitis is one of the most common and important surgical problem and its early diagnosis is very important. Diagnosis of appendicitis is based on clinical examination and laboratory tests. Therefore، we decided to take a small step in recognition of problems by evaluation of CRP and Platelet level in diagnosing of non-perforated and perforated appendicitis patients. This cross- sectional study was done on 160 patients with diagnosis of appendicitis on 2011. Patients were examined and then were operated in operation room by standard method. The patients were divided in two groups in terms of perforated and non-perforated appendicitis. Data were analyzed by SPSS software and related statistical tests. Of 160 patients، 124 patients (77. 5%) were male and others were female. Forty nine patients (30/6%) had perforated appendicitis and 111 patients (69/4%) non-perforated appendicitis. Mean age of participants in the perforated and non-perforated groups were 28. 35±20. 15 and 27. 75±21. 65 years، respectively. There was no significant difference between two groups regarding sex distribution، but risk of perforation increased by aging (odds ratio: 1. 1) CRP levels were significantly higher in the perforated group than non-perforated appendicitis group (p<0. 003)، but platelet levels were similar between two groups. This study showed that it is possible to use CRP for diagnosing of acute and perforated appendicitis، but it may never be replaced exact clinical examination and sonography.