Effect of exercise on sex-hormone rats with polycystic ovary syndrome

Weight gain andfataccumoulationare one of risk factors which led topolycystic ovarysyndrome. The aim of thisstudy was to examinethe effect ofexercise intensityonsexual hormonechanges inratswithpolycysticovary syndrome. 40 femaleWistarratswere selected (180±20mg) every2to 3consecutiveestrouscyclesduring12 to14 days. Thefirsttwogroupsweredivided into control (n = 30)andpolycystic(n = 30)that became patient byestradiolvalerateinjectionafter60 days. Thepolycysticgroupswere dividedinto threegroups of observer(n = 30), experiment group1 (low-intensity exercise (n = 30)) andexperiment group2 (moderate intensity exercise (n = 30)). Exercises were performed6 sessions of60 minutesper weekfor8 weeks.The mice were anesthetized by injection of 5 ml of blood directly from the heart and the blood factor measured by Elisa, ANOVAandLSDsamples were usedfor normal distributionsandKruskal-Wallis testfor analysis ofdata thatwere notnormally distributed. Concentrations of FS.Hin experiment group1increasedsignificantlycompared to thecontrol groupand the observer group. Also free testosterone was significantly higher compared to observer group. FSH concentration ingroup2 was higher ascompared to thecontrol and observer groups, and changestoLH,estrogenandandrostenedion were notsignificantcompared tothecontrol group despite theirincreased. Rightand leftovarianweightingroup1 had ahigherfinalweightandtotal weights of laboratory animals in research were notsignificant. According to weight changes and sexual hormones (FSH and Androstenedion)exercise training especially with low intensity may improvesymptomsof polycystic ovary syndrome.