The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis
Author(s):
Andreia Henriques , Regina Arantes , Rodrigues , Ana I. Faustino , Rocha , Catarina I. Teixeira , Guedes , Jacinta Pinho , Oliveira , Daniela Talhada , JosÉ H. Teixeira , Andreia Andrade , Bruno ColaÇo , Maria N. Paiva , Cardoso , Maria J. Pires , Ana Mvd Ferreira , Fernando M. Nunes , Paula A. Oliveira*
Abstract:
Objective(s)
effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials And Methods
The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) by gavage during 10 weeks and whole GT (0.5%) was provided ad libitum during 20 weeks. Results
Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion
We did not observe any effects by GT infusion administration on urinary bladder cancer development.Keywords:
Language:
English
Published:
Iranian Journal of Basic Medical Sciences, Volume:17 Issue: 2, Feb 2014
Pages:
145 to 148
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