Effect of resistance training on serum interleukin-18 and C-reactive protein in obese men

Previous studies have reported inconsistent findings about the effect of endurance training on level of interleukin-18 (IL-18) and high-sensitivity C-reactive protein (hsCRP) in obese individuals. This study was performed to determine the effect of resistance training on serum level of IL-18 and hsCRP in obese men. In this clinical trial، eighteen obese men were randomly divided into training and control groups. After 12-hours fasting، height، weight، body mass index، body fat percent، serum level of IL-18 and hsCRP were assessed before and after training period. Resistance training protocol consisted of twelve weeks training، 3 sessions training per week، each session for 60 minutes. Mean±SD of IL-18 were 323. 34±46. 57 pg/ml and 239. 43±53. 75 pg/ml in training and control groups، respectively. Mean±SD of hsCRP was 3. 83±3. 65 µg/ml and 3. 03±2. 98 µg/ml in training and control groups، respectively. This difference was not significant. Performing resistance training for twelve weeks did not significantly reduce IL-18 and hsCRP in obese men.