Acupoint catgut embedding therapy with moxibustion reduces the risk of diabetes in obese women

Obesity is a major health problem worldwide for which conventional therapy effi cacy is limited. Traditional Chinese medicine, particularly body acupoint stimulation, provides an alternative, eff ective, and safe therapy for this medical challenge. Th e present study was designed to compare the eff ects of distinct methods to stimulate the same set of acupoints, on anthropometric and biochemical parameters in obese women. Ninety-nine obese women were randomly assigned to six groups of treatment: Acupuncture with moxibustion, long needle acupuncture with moxibustion, electroacupuncture (EA), EA with moxibustion, embedded catgut with moxibustion (CGM) and sham acupuncture as control. Obesity-related parameters, including body weight, body mass index (BMI), waist and hip circumferences, waist/hip ratio, biochemical parameters (triglycerides, cholesterol, glucose, insulin) and homeostasis model of assessment - insulin resistance (HOMA-IR) index, were determined before and after each treatment. Body weight and BMI were signifi cantly reduced in response to all treatments. Interestingly, acupoint catgut embedding therapy combined with moxibustion was the only treatment that produced a signifi cant reduction in body weight (3.1 ± 0.2 kg, P < 0.001), BMI (1.3 ± 0.1 kg/m2, P < 0.001), insulin (3.5 ± 0.8 mcU/ml, P < 0.1) and HOMA-IR (1.4 ± 0.2 units, P < 0.01) in comparison with sham group. Furthermore, this treatment was able to bring back obese women to a state of insulin sensitivity, indicating that acupoint catgut embedding therapy combined with moxibustion could beuseful as a complementary therapy to reduce the risk of diabetes associated to obesity in women. Overall, our results confi rmed the eff ectiveness of acupoints stimulation to assist in the control of body weight in women. Th ey also highlighted the more favorable eff ects of embedded catgutmoxibustion combination that may be due to the extended and consistent stimulation of acupoints.