Voltammetric Determination of Parathion at Sulphonated Polyaniline based Electrochemical Sensor

A highly sensitive voltammetric method was developed for the determination of parathion in biological samples using sulphonatedpolyaniline modified glassy carbon electrode. The modified electrode was electrochemically fabricated by cyclic voltammetric method. Electrochemical reduction of parathion at modified electrode was investigated by cyclic voltammetry and differential pulse voltammetry. The instrumental parameters and reaction conditions were optimized for the development of stripping voltammetric procedure for the determination of parathion. A linear relationship was found between the peak current due to the reduction of nitro group to hydroxylamine and parathion concentration over the range from 1.0×10-8 to 2.0×10-5 M with detection limits of 1.5×10-9 M. The applicability of the proposed method was demonstrated by the determination of parathion in spiked human urine samples.