Association between Metabolic Syndrome and Coronary Artery Stent Stenosis

Stenosis of the stent is an explanatory outcome of successful results in patients under angioplasty procedures for coronary artery disease. Determination of the risk factors for this phenomenon is an important step for programming to reduce the stenosis rate and improving the outcomes. Hence, this study was performed to determine the association between the metabolic syndrome and stent restenosis. In this cross-sectional descriptive-comparative study, 122 patients with the acute coronary syndrome or chronic stable angina admitted to Shariati hospital, Tehran, Iran, between 2012 and 2014, who had a history of percutaneous coronary intervention (PCI) with coronary stent insertion were enrolled and the prevalence of in-stent stenosis and association with the metabolic syndrome were determined. There was no significant association between the metabolic syndrome and stent stenosis (P=0.129), and 21 (35%) patients and 14 (22.6%) individuals among those with and without the metabolic syndrome had in-stent stenosis. The mean duration of stent placement was 3.63 ± 1.51 and 2.99 ± 1.61 years in those with and without stent stenosis, respectively, showing a significant difference (P=0.046). Among those with dyslipidemia 48.6% and among the patients without dyslipidemia 20% had stenosis in the stent, showing a significant difference (P=0.001). We conclude that the metabolic syndrome is not a contributing factor for stent stenosis.