Antifungal Activity of Kiwi Alcoholic Extract on Saprophytes and Dermatophytes Fungi

Message:
Abstract:
Background And Objective
There are a few reports of antifungal activity of kiwi extract. This study was designed to investigate the antifungal activity of kiwi alcoholic extract on Saprophytes and Trichophyton mentagrophytes and Dermatophytes for the first time in Iran.
Materials And Methods
A Fungal suspension containing 1×105 CFU/mL of conidia and yeasty cells from 9 selected fungi was prepared in normal salin with tween 80 (0. 5%). In order to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of kiwi alcoholic extract، serial dilution of kiwi extract was prepared to Sabouraud Dextrose Broth medium. Candida spp and Aspergillus spp cultures were incubated at 30 and 25°C for 24-72 hours، respectively. Data was analyzed with chi-square and analysis of variance test and p<0. 05 considered as significance level.
Results
The ranges of percentage reduction in growth of dermatophyte and saprophytes were seen at a concentration of 10 and 20% in 24 and 48 hours، respectively. There were no significant differences between two groups (p>0. 05).
Conclusion
This study showed that alcoholic extract of kiwi fruit has anti-fungal property and this feature may depend on the type of fungus.
Language:
Persian
Published:
Journal of Rafsanjan University Of Medical Sciences, Volume:14 Issue: 2, 2015
Pages:
151 to 160
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