Effect of eight weeks high intensity aerobic training on adipocyte fatty acid-binding protein in obese middle-aged men

Adipocyte fatty acid-binding protein (A-FABP) is a plasma biomarker recently associated with the obesity. Exercise training may reduce the adipose tissue، although it is not truly known whether exercise–induced change in adipose tissue، decreases A-FABP concentrations or not; therefore the aim of this study was to investigate A-FABP concentrations in middle-aged men after 8 weeks high intensity aerobic training. Twenty two sedentary obese middle-aged men (age: 46. 4±2. 3 years، body mass index (BMI): 32. 8±2. 0 kg/m2 and maximum oxygen uptake: 34. 4±2. 6 ml. kg-1. min-1; mean±SD) volunteered to participate in this study. The subjects were randomly assigned to the training group (n=11) or control group (n=11). The training group performed high intensity aerobic training 3 days a week for 8 weeks at an intensity corresponding to 75-80% individual maximum oxygen consumption for 45 min. The results showed that the BMI and body fat percentage were decreased in the training group compared to the control group (p<0. 05). After 8 weeks of HIT، the training group resulted in a significant decrease (p<0. 05) in the A-FABP and insulin resistance compared with the control group. The results suggest aerobic training with the specific intensity and duration utilized in this study decreases A-FABP concentrations in obese middle-aged men.