CORRELATION BETWEEN COPPER AND IRON LEVELS WITH FASTING BLOOD GLUCOSE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND THEIR FIRST-DEGREE RELATIVES
Author(s):
Abstract:
Background and Aims
Metabolism of several trace elements such as copper and iron in diabetes mellitus has been changed which may have an important role in the pathogenesis and progression of the disease. The aim of this study was to evaluate association of serum copper and iron levels with fasting blood glucose (FBG) in patients with type 2 diabetes mellitus (T2DM) and their first-degree relatives (FDRs).Materials and Methods
We studied 46 subjects with T2DM, 46 FDRs and 50 healthy subjects matched for age and sex. Blood glucose and mentioned elements were measured in three groups with standard and colorimetric methods, respectively. The results were evaluated with one-way ANOVA test using statistical software SPSS 16. Correlations between different variables were analyzed using Pearsons correlation coefficients.Results
FBG levels were positively correlated with iron levels (r=0.650, PConclusion
Alterations in iron and copper concentrations in patients with type 2 diabetes mellitus and their first degree relatives may relate to blood glucose level, especially in the case of iron. It seems that it is useful to follow up the concentrations of these elements in diabetic patients and their first degree relatives.Keywords:
Language:
Persian
Published:
Journal of Medical Science Studies, Volume:26 Issue: 12, 2016
Pages:
1071 to 1079
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