Effective factors of treatment outcome in smear positive tuberculosis patients in Golestan province-Iran (2014)
Author(s):
Abstract:
Background And Objective
Tuberculosis (TB) is the main cause of death in the world. Half of the patient eventually will die during first 5-year of infection if they do not receive suitable treatment. According to WHOs report, treatment success in Iran is lower than the regional and global mean. This study was conducted to identify the effective factors of treatment failure among tuberculosis patient in golestan province- Iran.Methods
This cross- sectional study was conducted on 331 new smear positive tuberculosis patients that detected in TB laboratory in in golestan province-north of Iran during 2014. Inclusion criteria included weight more than 30kg, age greater than 13 years, diabetes, immune deficiency, liver or kidney diseases. Patients were treated according to a protocol for a period of two months on the DOTS strategy. The criterion of treatment outcome was sputum smear at the end of the second month of treatment. The effect of gender, medication regiment, age, weight, smoking, addiction and severity of smear basilli load on treatment outcome was assessed.Results
50.8% and 49.2% of patients were treated with combination and separate medicinal regiments, respectively. The conversion rate of smear positive was 67.7% at the end of the second months. According to multivariate logistic regression, the age of the patient (95% CI: 0.96-0.99, OR: 0.98, P=0.017), addiction (95% CI: 1.26-4.54, OR: 2.4, P=0.008), ethnicity (95% CI: 1.86-7.02, OR: 3.62, P=0.0001) and diagnostic smear bacilli load (PConclusion
The success of two months treatment was fairly low and the important factors on treatment success during the intensive phase were patient age, smoking, addiction and diagnostic smear bacilli load.Keywords:
Language:
Persian
Published:
Journal of Gorgan University of Medical Sciences, Volume:18 Issue: 2, 2016
Pages:
102 to 107
magiran.com/p1545533
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!