Response of Creatine Kinase and Lactate Dehydrogenase Enzymes to Rest-Interval Length Between Sets of Resistance Exercise in untrained men

The purpose of this study was to determine the effects of two resistance exercise protocol at different rest intervals on creatine kinase (CK) and lactate dehydrogenase (LDH). For this purpose, twenty untrained men (age 22.5±1.6 yr; high 174±3.4 cm; weight 73.2±3.5 kg) voluntarily participated in the research and randomly assigned in one of two resistance exercise group at rest intervals of 90 s (n=10) and 180 s (n=10). Resistance exercise was done with six repetitions maximum (85%1RM) in four sets. Blood samples were collected from the antecubital vein at pre exercise, immediately post exercise, 6, 24 and 48 hours post exercise. The results indicated that CK and LDH enzymes significantly increased at 24h post-exercise in both groups and continued for 48 hours’ post-exercise (P≤0.0001). But, there were no significant difference of interaction of time × resistance exercise in the CK (P=0.767) and LDH (P=0.250) between groups. It means rest interval between sets did not effect on changes mentioned enzymes. Generally, it can be concluded that rest time intervals between Sets in resistance exercises dont affect cellular damage.