suspected case of malignant hyperthermia following isofloran

Malignant hyperthermia is one of the contraindications to use succinylcoline and volatile inhalation anesthesia drugs also is a pharmacogenic disorder and life threat event. Clinical presentation mostly followed by hypermetabolism, rigidity of muscles and hyperthermia. The aim is presentation of a suspected case of malignant hyperthermia following isoflurane.
Patient presentation: The patient was 18 years of age and 60kg candidate of uretroscopy. Patient and his family did not report history of neuromuscular disease. The patient had not experienced anesthesia .Induction started by propofol and maintenance continued by O2, N2O, propofol and isoflurane. At the end of surgery muscles of patient was rigid in the recovery. Core temp increased rapidly and did 41 °c. Also acid-base disorder, tachycardia, tachypenea, increased ETCO2 were manifestations of malignant hyperthermia. Treatment comprised of dontrolene andsupportive cure.
Although muscle biopsy is diagnostic, however, treatment should be started with dantrolene and supportive care following manifestations to decrease complications. Recurrence of symptoms can occur up to 36 hours without any stimulas.