A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate: Casein phosphopeptide on early enamel lesion

This study was done to evaluate remineralizing potential of bioactive glasses (BAGs)and amorphous calcium phosphate‑casein phosphopeptide (ACP‑CPP) on early enamel lesion.
Twenty freshly extracted mandibular premolars were sectioned sagittally.The buccal half was impregnated in acrylic resin blocks and treated with 37% phosphoric acid inliquid form, to demineralize enamel surface to simulate early enamel lesion. The samples were dividedinto two groups. The samples in Group I were treated with ACP‑CPP (GC Tooth Mousse) and inGroup II with BAG (Sensodyne Repair and Protect) and stored in saliva to prevent dehydration.The samples were tested for microhardness.Statistical Analysis: The data obtained was analyzed using ANOVA post hoc multiple comparisonand independent sample t‑test and presented as a mean and standard deviation.
All the samples showed a decrease in the microhardness after demineralization.After application of remineralizing agents, Group II showed a highly significant increase in themicrohardness (P Both the remineralizing agents tested in this study can be considered effective inrepair and prevention of demineralization. BAG showed better results initially, but eventually bothhave similar remineralizing potential.