Neonatal Hepatoblastoma (A Case Report)

Heapatoblastoma is the most common primary malignant liver disease. It occures primarily in children younger than 3 years old. It is very rare in neonatal period.
Most children present with an enlarging, asymptomatic abdominal mass. Serum alpha fetoprotein is elevated in 66 percent of patients, significant thrombocytosis, mild anemia and moderate leukocytosis are also common. Abdominal X-Rays demonstrate hepatic enlargement with intratumor calcification in 30% of the cases. CT scan of abdomen and chest are essential for diagnosis because 10-20% of patients present with pulmonary metastasis. Angiography to delineate blood supply of tumor and MRI to visualize adjucent structures are helpful for surgical excision of tumor.
Excision of primary tumor by surgery and chemotherapy is the treatment of choice for this tumor before and after surgery .. The 3 years survival rate exceed 900A, in patients with completely resected tumors, at diagnosis.
In this article we are reporting a 22 days old neonate with hepatoblastoma.