Preparation and Characterization of Poly(Vinyl pyrrolidone)/Polyvinyl Chloride Coated Superparamagnetic Iron Oxide (Fe3O4) Nanoparticles for Biomedical Applications

Superparamagnetic Fe3O4 nanoparticles double coated with poly(vinylpyrrolidone)/polyvinyl chloride polymers were successfully fabricated by a facile cathodic electrochemical deposition (CED) method. In this method, in situ polymer coating ofthe surface of Fe3O4 nanoparticles was achieved through electrodeposition process. The evaluation by XRD analysis confirmed that the electrodeposited nanoparticles are composed of pure phase of iron oxide i.e. magnetite (Fe3O4). The structure and composition of the prepared nanoparticles were characterized by SEM, TEM, DLS, XRD, FTIR, and TG analysis. The DLS analysis revealed that the bare and prepared polymer coated Fe3O4 nanoparticles have size of 20nm and 62nm, respectively. The polymer coated nanoparticles with having 15nm in size, suitable magnetization value (Ms=22 emu/g), and negligible coercivity (Ce=0.42 emu/g) and remanence (Mr=1.1 Oe) are proper candidate for biomedical applications. This electrochemical strategy is proposed as facile and efficient for preparation and double coating of Fe3O4 nanoparticles.