Trace Elements Status in Sera of Patients with Allergic Asthma
Author(s):
Abstract:
Background
Asthma is a multifactorial disease and its severity varies with the inflammatory grade. There are conflicting reports about the roles of trace elements in asthma. This study examined the effects of zinc (Zn), copper (Cu), and selenium (Se) concentrations in sera of patients with allergic asthma attending Ghaem Hospital, Mashhad, Iran.Methods
Forty-nine patients, aged 10 to 50 years, with asthma in moderate or severe stages, and 24 healthy controls, were enrolled in this study. After demographic data collection and clinical evaluations, the subjects serum concentrations of Zn, Cu, and Se were measured via atomic absorbency.Results
Mean serum levels of Zn and Se in patients with allergic asthma were lower than in the healthy control group, but the Cu concentration in sera of patients with allergic asthma was slightly higher than healthy controls.Conclusion
Low levels of trace elements, specifically Zn, may have a role in the pathogenesis of allergic asthma; replacement of these elements may be an effective treatment.Keywords:
Language:
English
Published:
Reports of Biochemistry and Molecular Biology, Volume:5 Issue: 1, Oct 2016
Page:
3
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