Interaction effects of ethrel and Mevinolin on plastidic terpenoids of Cannabis sativa

In this investigation, we studied the effect of ethrel and mevinolin on levels of chlorophyll, carotenoids, &alpha-tocopherol and pyruvate and the major cannabinoids (tetrahydrocannabinol and cannabidiol) in Cannabis sativa at vegetative stage. In treated plant with 10 µM ethrel and mevinolin was observed an increase in chlorophyll a and b content compared to control plants. The most content of carotenoid was observed in mevinolin treated plant with 0.1 µM concentration. Ethrel could not increase carotenoid content more than carotenoid content in plant treated with mevinolin. Ethrel and Mevinolin increased &alpha-tocopherol content in comparison to control plant. In synchronic treatment of ethrel and mevinolin the most &alpha-tocopherol content was observed in 0.1 µM concentration of both treatment. Treatment with mevinolin and ethrel did not increase the amount of tetrahydrocannabinoid in cannabis plants. Only mevinolin increased cannabinoid content and usage of ethrel did not increase the amount of cannabinoid rather than plant treated with mevinolin. Special pattern was not observed in pyrovate content change in mevinolin, etherel and combined treatment. Base on our results, enhancement effect of ethrel in enhancement of plastidic terpenoids content in treated plants with mevinolin was visible in chlorophylls and &alpha-tocopherol content.