Comparison of the invasive pathological method and serological diagnosis of Helicobacter pylori in patients at Taleghani hospital in Chalous from 2014- 2015

Helicobacter pylori is the main etiology of peptic ulcers and chronic gastritis. The prevalence of Helicobacter pylori is typically higher in developing countries. The aim of this study was to determine the Prevalence compare of the invasive pathological method and serological diagnosis of Helicobacter pylori in patients at Taleghani hospital in Chalous from 2014- 2015
This study was performed on 358 patients who referred to Taleghani Hospital Branch from 2014 to 2015. For detection of H. pylori the gastric antrum and duodenal biopsies were done by pathological method and determine of the Antibody (IgG) were done by ELISA method.
Results and the results showed that the overall prevalence of H. pylori infection was 22.34% (80/358) and it was significantly higher in woman (30.06%) compared to man (15.89%) (p=0.001). The most prevalence was seen in 26-35 age group (30.8) and 71-80 weight group (36.1). The high prevalence of infection in the age group 35-26 years (30.8%), showed biopsy sampling of tissue staining is useful than serological test. This study showed that antibody titration alone is not sufficient for definitive diagnosis requires a biopsy is invasive sampling.