Aut ecology, ethnopharmacology,phytochemistry and antioxidant activity of Ferula gummosa Boiss. In different regions of Razavi Khorasan Province

Ferula gummosa Boiss. belongs to Apiaceae family is a perennial, endemic, monocarpic and useful medicinal-industrials plant in mountainous regions of Khorasan province. In this research and in many field observation different parts of Ferula gummosa (leaf, flower and root) were collected from two natural regions in Razavi Khorasan province (1760-2010 m), then ecological requirements and ethno pharmacology data were obtained and recorded by rural healer (67 years). Total phenol (TP) and total flavonoids (TF) of methanolic extracts were measured by spectrophotometery and antioxidant activity was measured by scavenging free radicals of DPPH. Results showed that the resin of the plant roots have been used by rural people as anti spasm, sedative and anti-infection to treat of migraine, dysmenorrheal and diarrhea. Total phenol and total flavanoid were reported 18.16 mg GAE g-1 and 15.20 mg QUE g-1, respectively and the highest content of antioxidant activity belonged to methanolic extract of flowers especially in Neishabour region (84.5%).