Immunogenicity of Bhk-Rabies Vaccine in Cattle
Author(s):
Abstract:
In this study, the immunogenicity of a rabies vaccine that was used in one of the Isfahan cattle farms is reported. This vaccine was produced by replication of the Pasteur virus (PV) strain on BHK-21 monolayer cell culture. The virus suspension was inactivated by ß-propiolactone treatment and the harvested pool showed sterility and safety. Thus, the obtained vaccine was tested on mice and a satisfactory immune response was observed. Thereafter, the vaccine was tested on 34 cattle divided into 2 groups. Each group was received a different dose of the vaccine intramuscularly. Sera were taken 2 months after rabies vaccination and were analyzed by the rapid fluorescence focus inhibition test (RFFIT) to evaluate the titer of the rabies-neutralizing antibody. Both groups under study showed a sufficient seroconversion.
Keywords:
Rabies , Anti , rabies vaccine , BHK , 21 cell , Cattle immunization
Language:
English
Published:
Iranian Biomedical Journal, Volume:4 Issue: 4, Oct 2000
Page:
129
magiran.com/p16794
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!