Effect of Vitamin E and Selenium on Oxidative Stress and Tissue Damages Induced by Electromagnetic Fields in Immature Mice Ovarian

Electromagnetic fields (EMF) due to increased oxidative stress impact on body systems including female reproductive system and reduce fertility. The use of antioxidants decreases the amount of damage through the oxidative stress reduction. The present research studies the effect of vitamin E and selenium on oxidative stress factors level resulting from EMF in immature mice ovarian tissue.
Material and In this study, 48 immature mice were randomly divided into 6 groups (n=8): (1) control, (2) EMF, (3) EMF with Vitamin E, (4) EMF with selenium, (5) EMF with vitamin E and selenium and (6) vitamin E and selenium. Finally, after 2 months the mice were killed by cervical dislocation and the ovaries were removed to evaluate tissue damages and oxidative stress factors including malondialdehyde (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD) and total antioxidant (TAC).
In mice under EMF, MDA level increased and SOD, GPX and TAC decreased in ovarian tissue (P The results of this study indicated that vitamin E and selenium plus vitamin E significantly reduced oxidative stress in ovarian tissue of the mice exposed to EMF, but prescribing selenium alone had no significant effect.