The Comparison of Eight Weeks Interval and Continuous Training on PRO-BNP/ CORIN System in Coronary Artery Disease Patients after CABG Surgery

The purpose of this study was the comparison effect of eight weeks continuous and interval training on PRO- BNP/CORIN system in coronary artery disease patients after CABG surgery. 36 patients were selected purposive (27 men and 9 women with mean of age 60.32±5.81 year, height 164.64 ± 9.25 cm, weight 73.86±14.23 kg, fat 32.30±4.28, SBP 142.67± 6.49 , DBP 84.5±5.16 mmhg in seated position at rest situation and functional capacity of 7.08±2.49 METs) and then divided randomly into three groups: control (C) group (without training program) aerobic continuous (AC) training and aerobic interval (AI) training (exercise training program was performed 3 day/week for 8 weeks) with intensities 65% to 80% and 80% to 95% of reserve heart rate in order. 48 hours before the first session of training program and after the final training session blood samples were collected. wilcoxin and kruskal wallis tests were used for analyzing data. Results indicate that PRO-BNP is increased, CORIN is decreased and BNP also is decreased significantly in (C) group (P=0.005,0.012,0.003). In both (AC) and (AI) groups, PRO-BNP is decreased, CORIN is increased and BNP also is decreased but these variations was significant only in AI group (P=0.005,0.002,0.002). Between group analyze also indicated that there is significant difference between groups in variation of PRO-BNP, CORIN and BNP (P≤0.001). (AI) training in contrast of (AC) training is more effective in PRO-BNP/­­CORIN system development after CABG.