Effect of Aerobic Training Program with Moderate Intensity on Liver Aminotranspherase Activity in Sedentary adult Obese Women

Obesity is an established risk factor for fatty liver and metabolic syndrome. The aim of the study was to investigate the effect of aerobic training on liver aminotranspherase activity (AST, ALP) and alkaline phosphatase (ALP) in adult obese women.
In this semi-experimental study, twenty eight sedentary adult obese females (36≤BMI≤36) were randomly divided into exercise (n=14) and control (n=14) groups. Exercise subjects were participated in 12-weeks aerobic training program, 3 times per week at 60-75% of HRmax. Pre and post training AST, ALT and ALP activity as well anthropometrical indexes were measured at 2 groups and compared with independent-paired T test. A significant level of 0.05 was considered.
At baseline, no significant differences were observed between groups in liver enzymes activity and anthropometrical indexes (P>0.05). Compared to pre training, despite no change in ALP activity (P≥0.114), a significant decrease were observed in activity of AST (P≤0.023) and ALT (P≤0.011) by aerobic program in exercise group. Aerobic training resulted in significant decrease in anthropometrical indexes of exercise subjects (P≤0.05). There were no changes in these variables between pre and post training in the control group (P≥0.05).
The supervised aerobic training provides an effective and safe treatment on liver enzymes activity in obese women. These benefits could be attributed to decreased fatty tissue especially abdominal fat by training intervention in obese subjects.