Effects of eight weeks of resistance training on serum SFRP5 concentration in obese men

Secreted frizzled-related protein 5 (SFRP5), like adiponectin, is considered as a novel adipokine with insulin-sensitizing and anti-inflammatory characteristics. The purpose of this study was to investigate the effect of eight weeks of resistance training on serum SFRP5 concentration in obese men.

Twenty four obese men (age; 36.9 ± 8.5 yr, weight; 94.8 ± 10.7 kg, and BMI; 31.7 ± 2.4) voluntarily participated in this study and were divided into control and resistance training groups (n=12). Subjects in training group performed eight weeks resistance training in a circuit manner with 50-85% 1RM (3 days/week). Anthropometrics parameters and fasting serum glucose, insulin, and SFRP5 concentrations, as well as insulin resistance index (HOMA-IR) were measured at the baseline and at the end of study.

Resistance training induced significant reductions in body weight, BMI, body fat percentage, waist and hip circumferences (P

It seems that resistance training could improve metabolic conditions at least by preventing a decrease in serum SFRP5 levels.