Relapsing Kaposi's varicelliform eruption in a patient with Darier's disease

Darier’s disease results from abnormal keratinization of skin and is characterized by numerous keratotic papules that preferentially involve seborrheic areas. Kaposi’s varicelliform eruption (KVE) occurs by viral infections such as herpes simplex virus (HSV) in some inflammatory skin disorders like Darier’s disease. Herein, we describe a 68-year-old man, a known case of Darier’s disease, who presented with a sudden appearance of umbilicated vesiculopustular lesions on the face, trunk, and extremities.
Diagnosis of KVE was confirmed by Tzanck smear and skin biopsy. Although the lesions resolved after oral acyclovir administration, the patient had recurrent episodes of KVE less
than one month later.