The relationship between the serum levels of copper and zinc and brucellosis disease

Brucellosis is a zoonotic disease in humans and animals and a public health problem throughout the world. Given that measuring changes in the levels of trace elements is a good marker for the diagnosis of infectious diseases from non-infectious ones, the aim of this study was to examine the relationship between the serum levels of copper and zinc and brucellosis.
This cross-sectional study was conducted on 100 patients with the brucellosis disease and the subjects were divided into two groups of case and control (n=50 in each group). The serum levels of copper and zinc were measured using the automatic absorptive spectrophotometer.
From a total of 100 patients, 31 patients (31%) were females and 69 (69%) were males. The mean age of the patients in the case group was 32.74±13.7 years and in the control group was 33.44±13.6 years. The results showed that the serum copper level was significantly increased and the zink level significantly decreased in the patients with brucellosis (P It seems that the serum levels of copper and zinc can be used as a valid marker for the diagnosis of brucellosis.