Tungsten oxide (WO3) Modified Carbon Paste Electrode for Electrochemical Investigation of Dopamine in Presence of Uric Acid and Folic Acid

Present work describes the synthesized and characterization of tungsten oxide nanoparticles (WO3NPs) was prepared by using tungsten carbide (WC). The prepared material was characterized by using X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscope (TEM) and infrared spectroscopy (IR). The prepared WO3NPs was used as the modifier for the preparation of carbon past electrode (WO3NPs/MCPE). The fabricated WO3NPs/MCPE exhibits an excellent electrocatalytic activity towards the dopamine (DA) in the presence of uric acid (UA) and folic acid (FA) in 0.2M phosphate buffer solution (PBS) of pH 7.4 by cyclic voltammetric (CV) and differential pulse voltammetric techniques (DPV). From the effect of scan rate, concentration and pH of the electrode phenomenon was confirmed to be adsorption-controlled process. The lower detection limit of dopamine was 0.58 µM, and the simultaneous analysis shows a good result with peak to peak separation between dopamine and other two analytes uric acid and folic acid by DPV techniques.