In Vivo Assessment of Gamma Rays, Electron-beam Irradiation plus a Commercial Toxin Binder (Milbond-TX) As an Anti-Aflatoxin B1 in a Chicken Model
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
Aspergillus flavus is the most important fungus for production of Aflatoxin B1 (AFB1). This study evaluated the ability of gamma rays (GRs) and electron-beam irradiation (EBI) to counteract the deleterious effects of aflatoxin B1 (AFB1) in a chicken model.Methods
Overall, 168 one-day-old male Coturnix quails were assigned to eight treatments for 42 d in Tehran, Iran, in 2010 and 2011. Two dietary inclusion rates of AFB1 (0 and 2 ppm) and toxin binders, such as 0, 27 kGy doses of GRs, 27 kGy doses of EBI, and 0.3% of commercial toxin binder-milbond-TX, were tested in a 2×4 factorial manner. Serum biochemical parameters, immune response, and dietary treatments on factors associated with kidney and lipid profiles were determined on day 42.Results
AFB1 significantly decreased the hematological parameters (Hematocrit in 21 and 42 d), immune response (White blood cell (WBC), heterophil to lymphocyte ratio (H/L) and sheep red blood cell (SRBC)), and blood chemical factors (glucose, albumin, total protein, and triglycerides) compared to the control diet (PConclusion
The addition of these toxin binders may reduce the adverse effects produced by the presence of AFB1 in Japanese quails diets.Keywords:
Aflatoxin B1 , Electron , Beam Irradiation , Gamma Rays , Japanese Quail , Milbond , TX
Language:
English
Published:
Iranian Journal of Toxicology, Volume:12 Issue: 2, Mar-Apr 2018
Pages:
15 to 20
magiran.com/p1796412
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