investigation and comparison of Information processing speed between three different subtypes of multiple sclerosis and healthy control subjects

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
Multiple Sclerosis (MS), as one of the most common neurological diseases of the central nervous system, is associated with various cognitive impairments. The purpose of this study was the investigation and comparison of the information processing speed between various clinical subtypes of multiple sclerosis and compared to healthy individuals.
Methods
In this cross-sectional study, 22 healthy volunteers, 21 relapsing-remitting MS, 8 primary progressive MS, and 21 secondary progressive MS patients were matched by age, gender and level of education with each other and the information processing speed was investigated using designed Deary-Liewald software and were analyzed and compared using analysis of variance (ANOVA).
Results
The results of ANOVA revealed that data processing speed was different at least between two groups (p0.05). Healthy subjects compared to primary progressive and secondary progressive have significant difference (p>0.05). There was no significant difference between other subtypes of multiple sclerosis (p>0.05).
Conclusion
The progressive MS subtypes, specially the secondary progressive subtype, have slower movement information processing compared to healthy subjects and other MS subtypes, and in the comparison of MS subtypes there was no significant difference.
Language:
Persian
Published:
Razi Journal of Medical Sciences, Volume:24 Issue: 10, 2018
Pages:
12 to 18
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