The effect of turmeric extract and sodium bentonite on some biochemical parameters in rats contaminated with Aflatoxin B1

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
Aflatoxins are a group of mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus and are an important factor in oxidative damage to the kidney and liver.
Objectives
The purpose of this study was to evaluate the effects of turmeric extract and/or sodium bentonite against renal and hepatic damage induced by aflatoxin B1.
Methods
In this experiment that lasted for four weeks 64 male Wistar rats randomly assigned to eight groups containing: control, aflatoxin (AF), turmeric extract (TE), sodium bentonit (SB), TE, AF, AF, AF(TE). At the end of experiment blood samples were taken from heart and some biochemical analysis has been performed.
Results
In the AF group, the levels of alanine aminotransferase (ALT), alkaline phosphatase (ALP), low density lipoprotein (LDL) and creatinine (P
Conclusions
According to the present research, it seems that TE and SB alone decrease the harmful effects of Aflatoxin B1 and the combination of them has a potentiating effect.
Language:
Persian
Published:
Journal of Veterinary Research, Volume:72 Issue: 3, 2017
Pages:
353 to 361
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