Comparison of Color Vision in Patients with Multiple Sclerosis

This study aimed to quantitatively assess the color vision in patients with relapsing and remitting multiple sclerosis with and without visual symptoms using D15.
In this study, 100 eyes of 50 patients with Multiple Sclerosis including 30 patients with visual symptoms and 20 patients without visual symptoms were compared with 50 eyes as the control group. Patients were divided into 4 groups: An involved eye of the patient with unilateral visual symptoms (group 1), fellow eye of the patient with unilateral visual symptoms (group 2), patient’s eye without visual symptoms (group 3), and eyes of the comparison group (group 4). Visual acuity was measured in log MAR. Color vision was evaluated using D15. The results were quantitatively recorded based on Color Confusion Index (CCI).
The meanCCI of color vision was 131.17±19.69 in the first group, 126.39±15.31 in the second group, 123.62±10.03 in the third group, and 117 in the fourth group. There was a significant difference between three groups and the control group. (p Color vision disorder has been observed in patients with and without visual symptoms; however, the severity of the defect was different between groups. Quantitative assessment of the color vision test provides useful information of the natural history of the disease for examiner. In addition, there are appropriate clinical criteria to identify subclinical defects along with other diagnostic methods in patients with MS.